Toxoplasma gondii expresses two distinct lactate dehydrogenase homologous genes during its life cycle in intermediate hosts

Two Toxoplasma gondii genes were characterized that are differentially expressed during the parasite's life cycle. The genes named LDH1 and LDH2, respectively, encode polypeptides similar to the enzyme lactate dehydrogenase (LDH; l-lactate:NAD + oxidoreductase, EC 1.1.1.27) from a variety of or...

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Veröffentlicht in:	Gene 1997-01, Vol.184 (1), p.1-12
Hauptverfasser:	Yang, Shumin, Parmley, Stephen F
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Apicomplexan parasite Base Sequence Blotting, Northern Bradyzoite cDNA cloning Chloramphenicol O-Acetyltransferase - genetics Chloramphenicol O-Acetyltransferase - metabolism Cloning, Molecular Codon - genetics Developmental gene expression Electrophoresis, Gel, Two-Dimensional Gene Expression Regulation, Developmental - genetics Genes, Reporter Immunoblotting Isoenzymes L-Lactate Dehydrogenase - chemistry L-Lactate Dehydrogenase - genetics Molecular Sequence Data RNA, Messenger - genetics RNA, Messenger - metabolism Sequence Alignment Sequence Analysis Tachyzoite Toxoplasma - enzymology Toxoplasma - genetics Toxoplasma gondii
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