Infusion of pramlintide, a human amylin analogue, delays gastric emptying in men with IDDM

Pramlintide, a human amylin analogue, reduces hyperglycaemia after meals in patients with insulin-dependent diabetes mellitus (IDDM). We investigated whether this was due to delayed gastric emptying. Eight men with uncomplicated IDDM were studied twice in a randomised, double-blind crossover design....

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Veröffentlicht in:	Diabetologia 1997-01, Vol.40 (1), p.82-88
Hauptverfasser:	KONG, M.-F, KING, P, MACDONALD, I. A, STUBBS, T. A, PERKINS, A. C, BLACKSHAW, P. E, MOYSES, C, TATTERSALL, R. B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amyloid - administration & dosage Amyloid - therapeutic use Biological and medical sciences Blood Glucose - analysis Blood Glucose - metabolism Cross-Over Studies Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - drug therapy Diabetes Mellitus, Type 1 - physiopathology Double-Blind Method Food Gastric Emptying - drug effects Gastric Emptying - physiology General and cellular metabolism. Vitamins Humans Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - therapeutic use Infusions, Intravenous Insulin - blood Insulin - metabolism Islet Amyloid Polypeptide Male Medical sciences Pharmacology. Drug treatments Time Factors
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