Hippocampal Atrophy Is Not a Major Determinant of Regional Hypometabolism in Temporal Lobe Epilepsy

Purpose: The pathophysiologic basis for the [18F]fluorodeoxyglucose positron‐emission tomography (FDG‐PET) temporal lobe hypometabolism in patients with hippocampal sclerosis (HS) is uncertain. We tested the hypothesis that hippocampal atrophy, which is strongly correlated with hippocampal cell loss...

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Veröffentlicht in:	Epilepsia (Copenhagen) 1997-01, Vol.38 (1), p.74-80
Hauptverfasser:	O'Brien, T. J., Newton, M. R., Cook, M. J., Berlangieri, S. U., Kilpatrick, C., Morris, K., Berkovic, S. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Atrophy Basal Ganglia - diagnostic imaging Basal Ganglia - metabolism Basal Ganglia - pathology Biological and medical sciences Brain - diagnostic imaging Brain - metabolism Brain - pathology Deoxyglucose - analogs & derivatives Epilepsy, Temporal Lobe - diagnostic imaging Epilepsy, Temporal Lobe - metabolism Epilepsy, Temporal Lobe - pathology FDG‐PET Female Fluorodeoxyglucose F18 Functional Laterality Glucose - metabolism Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Hippocampal atrophy Hippocampus - diagnostic imaging Hippocampus - pathology Humans Hypometabolism Magnetic Resonance Imaging Male Medical sciences Middle Aged Nervous system (semeiology, syndromes) Neurology Temporal Lobe - diagnostic imaging Temporal Lobe - metabolism Temporal Lobe - pathology Temporal lobe epilepsy Thalamus - diagnostic imaging Thalamus - metabolism Thalamus - pathology Tomography, Emission-Computed Volumetric MRI
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