Biochemical effects of estrogen on articular cartilage in ovariectomized sheep

Cartilage is a sex-hormone-sensitive tissue but the role of estrogen in the pathogenesis of osteoarthritis (OA) remains controversial. In this study, intrinsic material properties and thickness of articular cartilage of the knee joint of ovariectomized (OVX) and estrogen-treated sheep were measured....

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Veröffentlicht in:	Osteoarthritis and cartilage 1997, Vol.5 (1), p.63-69
Hauptverfasser:	Turner, A. Simon, Athanasiou, Kyriacos A., Zhu, Chong-Fang, Alvis, Mark R., Bryant, Henry U.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Articular cartilage Biphasic theory Cartilage, Articular - drug effects Cartilage, Articular - physiology Compressive Strength Estradiol - blood Estradiol - pharmacology Estrogen Female Knee Joint - physiology Luteinizing Hormone - blood Material properties Ovariectomy Sheep
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