Expression of the RET/PTC Fusion Gene as a Marker for Papillary Carcinoma in Hashimoto's Thyroiditis

Hashimoto's thyroiditis is an inflammatory disease of the thyroid gland with autoimmune etiology.1 Patients afflicted with Hashimoto's have a higher risk of thyroid malignancies such as papillary thyroid carcinoma.2 In the present study, we investigated the frequency of papillary thyroid c...

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Veröffentlicht in:	The Laryngoscope 1997-01, Vol.107 (1), p.95-100
Hauptverfasser:	Wirtschafter, Ari, Schmidt, Richard, Rosen, David, Kundu, Nandita, Santoro, Massimo, Fusco, Alfredo, Multhaupt, Hinke, Atkins, Joseph P., Rosen, Marc R., Keane, William M., Rothstein, Jay L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Biomarkers, Tumor - genetics Carcinoma, Papillary - complications Carcinoma, Papillary - genetics DNA Primers Drosophila Proteins Endocrinopathies Female Gene Expression Hashimoto's thyroiditis Humans Male Malignant tumors Medical sciences Middle Aged Oncogene Oncogene Proteins - genetics Papillary thyroid carcinoma Polymerase Chain Reaction - methods Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins c-ret Receptor Protein-Tyrosine Kinases - genetics RET/PTC fusion gene RNA, Messenger - genetics RNA, Messenger - isolation & purification RNA-Directed DNA Polymerase Thyroid gland Thyroid Neoplasms - complications Thyroid Neoplasms - genetics Thyroid. Thyroid axis (diseases) Thyroiditis, Autoimmune - complications Thyroiditis, Autoimmune - genetics
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