Regulation of intracellular chloride concentration in rat lactotrophs: possible role of mitochondria

Increasing evidence is accumulating for the involvement of chloride ions in the stimulus-secretion coupling of pituitary cells. We show that the mean intracellular chloride concentration [Cl −]i of rat lactotroph cells maintained in culture is high, close to 60 mM (59.4 mM), using the Cl − sensitive...

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Veröffentlicht in:	FEBS letters 1997-01, Vol.400 (1), p.113-118
Hauptverfasser:	Garcia, L, Rigoulet, M, Georgescauld, D, Dufy, B, Sartor, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured Chlorides - metabolism Electrochemistry Electrophysiology Female Fluorescent Dyes Intracellular chloride concentration Intracellular Membranes - drug effects Lactation Metabolic inhibitor Microspectrofluorimetry Mitochondria - drug effects Mitochondria - metabolism Mitochondrial chloride store Patch-Clamp Techniques Pituitary Gland, Anterior - cytology Pituitary Gland, Anterior - metabolism Quinolinium Compounds Rat lactotroph Rats Rats, Wistar Uncoupling Agents - pharmacology
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