Mechanical Strain Tightly Controls Fibroblast Growth Factor-2 Release From Cultured Human Vascular Smooth Muscle Cells

Although fibroblast growth factor-2 (FGF-2) participates in the response to vascular injury, the role of cellular deformation in FGF-2 release is incompletely understood. To test the hypothesis that mechanical strain tightly controls FGF-2 release, a novel device was used to impose homogeneous and u...

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Veröffentlicht in:	Circulation research 1997-01, Vol.80 (1), p.28-36
Hauptverfasser:	Cheng, George C, Briggs, William H, Gerson, David S, Libby, Peter, Grodzinsky, Alan J, Gray, Martha L, Lee, Richard T
Format:	Artikel
Sprache:	eng
Schlagworte:	Cells, Cultured Cytoplasm - metabolism Fibroblast Growth Factor 2 - metabolism Humans Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - metabolism Receptors, Cell Surface - metabolism Space life sciences Stress, Mechanical
Online-Zugang:	Volltext
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