Comparative molecular field analysis-based predictive model of structure-function relationships of polyamine transport inhibitors in L1210 cells

Maintenance of intracellular polyamine concentrations necessary for cell growth and proliferation is regulated in part by an energy-dependent polyamine uptake system. To obtain information on the characteristics of the polyamine uptake system in L1210 leukemia cells, we have applied computational ch...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1997-01, Vol.57 (2), p.234-239
Hauptverfasser:	LI, Y, MACKERELL, A. D, EGORIN, M. J, BALLESTEROS, M. F, ROSEN, D. M, WU, Y.-Y, BLAMBLE, D. A, CALLERY, P. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences General aspects Leukemia L1210 - metabolism Medical sciences Mice Models, Chemical Pharmacology. Drug treatments Polyamines - antagonists & inhibitors Polyamines - chemistry Polyamines - metabolism Spermidine - antagonists & inhibitors Spermidine - chemistry Spermidine - metabolism Structure-Activity Relationship
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!