Delayed occurrence of enhanced striatal preprodynorphin gene expression in behaviorally sensitized rats : Differential long-term effects of intermittent and chronic morphine administration

Protracted changes in basal "steady-state" opioid peptide gene expression in the brain may represent adaptations underlying the behavioral effects of drugs of abuse, observed long after drug exposure. Here, we have studied the long-term effects of two distinct regimens of morphine administ...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience 1997, Vol.76 (1), p.167-176
Hauptverfasser:	TJON, G. H. K, VOORN, P, VANDERSCHUREN, L. J. M. J, DE VRIES, T. J, MICHIELS, N. H. L. M, JONKER, A. J, KLOP, H, NESTBY, P, MULDER, A. H, SCHOFFELMEER, A. N. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoradiography Behavior, Animal - drug effects Biological and medical sciences Corpus Striatum - physiology Drug addictions Dynorphins - genetics Enkephalins - genetics Gene Expression - drug effects Male Medical sciences Morphine - administration & dosage Morphine - pharmacology Motor Activity - drug effects Narcotics - administration & dosage Narcotics - pharmacology Protein Precursors - genetics Rats Rats, Wistar Time Factors Tissue Distribution Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!