Continued malignant cell proliferation in head and neck tumors during cytotoxic therapy

The effect of cytotoxic therapy on the proliferation of squamous cell carcinoma of the head and neck in vivo in patients was evaluated before and 15-35 days after the start of therapy. To accomplish this, iododeoxyuridine was administered at t = 0, and bromodeoxyuridine was administered 15-35 days l...

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Veröffentlicht in:	Clinical cancer research 1996-09, Vol.2 (9), p.1453-1460
Hauptverfasser:	H D Preisler, V M Kotelnikov, S LaFollette, S Taylor, 4th, S Mundle, N Wood, J S Coon, 4th, J Hutchinson, W Panje, D D Caldarelli, K Griem
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols Apoptosis - drug effects Apoptosis - radiation effects Biological and medical sciences Biopsy Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - therapy Cell Count - drug effects Cell Count - radiation effects Cell Division - drug effects Cell Division - radiation effects Chemotherapy Cisplatin - therapeutic use Combined Modality Therapy Female Fluorouracil - therapeutic use Head and Neck Neoplasms - metabolism Head and Neck Neoplasms - pathology Head and Neck Neoplasms - therapy Humans Immunohistochemistry Male Medical sciences Middle Aged Mouth Mucosa - drug effects Mouth Mucosa - pathology Mouth Mucosa - radiation effects Paclitaxel - therapeutic use Pharmacology. Drug treatments S Phase Time Factors
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