Semisynthetic Preparation of 1-O-hexadecyl-2-acetyl-sn-glyceryl-3- phosphorylcholine (Platelet Activating Factor)

1-O-hexadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (platelet activating factor, PAF), (1.9 μmol) was prepared from the total lipid extract of the protozoan Tetrahymena pyriformis 9 × 10 cells. The procedure involved mild alkaline hydrolysis of the total lipids, followed by acetylation and purifi...

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Veröffentlicht in:	Zeitschrift für Naturforschung C. A journal of biosciences 1988-10, Vol.43 (9), p.665-670
Hauptverfasser:	Lekka, Marilena E., Tsoukatos, Demokritos C., Tselepis, Alexandras D., Kapoulas, Vassilios M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Platelets - drug effects Blood Platelets - physiology Chromatography, Gas Chromatography, High Pressure Liquid - methods Ether Lipids Lipids - isolation & purification Phospholipids Platelet Activating Factor Platelet Activating Factor - chemical synthesis Platelet Activating Factor - isolation & purification Platelet Activating Factor - pharmacology Platelets Rabbits Tetrahymena - metabolism Tetrahymena pyriformis
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