The PRINS technique: potential use for rapid preimplantation embryo chromosome screening

The primed in-situ labelling (PRINS) method is an alternative to in-srtu hybridization for chromosomal detection based on the use of chromosome-specific oligonucleotide primers. Using this process, we have developed a simple and semi-automatic method for rapid in-situ detection of human chromosomes....

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Veröffentlicht in:	Molecular human reproduction 1996-02, Vol.2 (2), p.135-138
Hauptverfasser:	Pellestor, Franck, Girardet, Anne, Andréo, Brigitte, Lefort, Geneviéve, Charlieu, Jean Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Blastocyst - cytology Blastocyst - ultrastructure Blastomeres - ultrastructure Chromosome Aberrations - diagnosis Chromosome Disorders Chromosomes, Human - ultrastructure Cytodiagnosis - methods DNA Primers DNA, Satellite Fertilization in Vitro Fluorescent Dyes Genetic Markers Genetic Testing - methods human pre-embryo Humans In Situ Hybridization - methods in-situ labelling oligonucleotide Polymerase Chain Reaction preimplantation diagnosis PRINS
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