Evidence for inhibitory activity against cell proliferation in bovine liver

Bovine calf liver was homogenized in 0.1M NH 4Ac, pH 7.4, and centrifuged. The supernatant was lyophilized and resuspended in 44 mM NaHCO 3. After size exclusion chromatography on sephacryl S-300, a fraction of approximately 100 to 160 kDa was shown to inhibit the proliferation of rat L6 myoblasts i...

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