The somatosensory evoked potential predicts neurologic deficits and serotonergic pathochemistry after spinal distraction injury in experimental scoliosis
The validity of the somatosensory evoked potential as an intraoperative spinal cord monitor was evaluated in an experimental model of scoliosis in the rat and a Harrington distraction model of injury. Under these conditions, it was found that any change in latency or amplitude of the major negative...
Gespeichert in:
| Veröffentlicht in: | Journal of neurotrauma 1988, Vol.5 (3), p.173-186 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 186 |
|---|---|
| container_issue | 3 |
| container_start_page | 173 |
| container_title | Journal of neurotrauma |
| container_volume | 5 |
| creator | SALZMAN, S. K DABNEY, K. W MENDEZ, A. A BEAUCHAMP, J. T DALEY, J. C FREEMAN, G. M FONSECA, A INGERSOLL, E. B BECKMAN, A. L BUNNELL, W. P |
| description | The validity of the somatosensory evoked potential as an intraoperative spinal cord monitor was evaluated in an experimental model of scoliosis in the rat and a Harrington distraction model of injury. Under these conditions, it was found that any change in latency or amplitude of the major negative wave above a certain level was a significant predictor of an adverse neurologic outcome. Changes in latency of 4% or greater and changes in amplitude of 50% or greater were unequivocal indicators of spinal cord injury. Postmortem analyses of the spinal neurotransmitter serotonin revealed that apparent false-positive results of the SEP were, in fact, true-positive results. |
| doi_str_mv | 10.1089/neu.1988.5.173 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78742390</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>78742390</sourcerecordid><originalsourceid>FETCH-LOGICAL-c234t-a8baa92e717e278b0dcc2d7eb86d44636d65ca7d9b4e55665d734a32eb8bdbcd3</originalsourceid><addsrcrecordid>eNo9kUFv1DAQha0KVLaFa29IPiBuCbEd28kRVQUqVeJSzpZjT7ouWTt4HER_Cv-2XnXV00jzvnkzmkfIFeta1g3jlwhby8ZhaGXLtDgjOyalbsau52_IrgK60Uyyd-QC8bHrmFBcn5NzwXulRr4j_-_3QDEdbEkIEVN-ovA3_QZP11QglmAXumbwwRWkdVdOS3oIjnqYgwu1Z6OnCDmVFCEfldWWfXJ7OAQs1c3OBTLFNcTq5I8960pIkYb4uFU9RAr_VsjhULdVBF1aQsKA78nb2S4IH071kvz6dnN__aO5-_n99vrrXeO46Etjh8nakYNmGrgeps47x72GaVC-75VQXklntR-nHqRUSnoteit4BSY_OS8uyecX3zWnPxtgMfVyB8tiI6QNjR50z8XYVbB9AV1OiBlms9arbX4yrDPHLEz9jzlmYaSpWdSBjyfnbTqAf8VPz6_6p5Nu0dllzja6gK-YGoTSNbFnImuY2w</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>78742390</pqid></control><display><type>article</type><title>The somatosensory evoked potential predicts neurologic deficits and serotonergic pathochemistry after spinal distraction injury in experimental scoliosis</title><source>Mary Ann Liebert Online Subscription</source><source>MEDLINE</source><creator>SALZMAN, S. K ; DABNEY, K. W ; MENDEZ, A. A ; BEAUCHAMP, J. T ; DALEY, J. C ; FREEMAN, G. M ; FONSECA, A ; INGERSOLL, E. B ; BECKMAN, A. L ; BUNNELL, W. P</creator><creatorcontrib>SALZMAN, S. K ; DABNEY, K. W ; MENDEZ, A. A ; BEAUCHAMP, J. T ; DALEY, J. C ; FREEMAN, G. M ; FONSECA, A ; INGERSOLL, E. B ; BECKMAN, A. L ; BUNNELL, W. P</creatorcontrib><description>The validity of the somatosensory evoked potential as an intraoperative spinal cord monitor was evaluated in an experimental model of scoliosis in the rat and a Harrington distraction model of injury. Under these conditions, it was found that any change in latency or amplitude of the major negative wave above a certain level was a significant predictor of an adverse neurologic outcome. Changes in latency of 4% or greater and changes in amplitude of 50% or greater were unequivocal indicators of spinal cord injury. Postmortem analyses of the spinal neurotransmitter serotonin revealed that apparent false-positive results of the SEP were, in fact, true-positive results.</description><identifier>ISSN: 0897-7151</identifier><identifier>EISSN: 1557-9042</identifier><identifier>DOI: 10.1089/neu.1988.5.173</identifier><identifier>PMID: 3246692</identifier><identifier>CODEN: JNEUE4</identifier><language>eng</language><publisher>Larchmont, NY: Liebert</publisher><subject>Animals ; Biological and medical sciences ; Disease Models, Animal ; Evoked Potentials, Somatosensory ; Male ; Medical sciences ; Nervous System Diseases - etiology ; Nervous System Diseases - metabolism ; Nervous System Diseases - physiopathology ; Orthopedic surgery ; Rats ; Rats, Inbred Strains ; Reaction Time ; Scoliosis - complications ; Scoliosis - metabolism ; Scoliosis - physiopathology ; Serotonin - metabolism ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><ispartof>Journal of neurotrauma, 1988, Vol.5 (3), p.173-186</ispartof><rights>1990 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c234t-a8baa92e717e278b0dcc2d7eb86d44636d65ca7d9b4e55665d734a32eb8bdbcd3</citedby><cites>FETCH-LOGICAL-c234t-a8baa92e717e278b0dcc2d7eb86d44636d65ca7d9b4e55665d734a32eb8bdbcd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,3029,4010,27900,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6836701$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3246692$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SALZMAN, S. K</creatorcontrib><creatorcontrib>DABNEY, K. W</creatorcontrib><creatorcontrib>MENDEZ, A. A</creatorcontrib><creatorcontrib>BEAUCHAMP, J. T</creatorcontrib><creatorcontrib>DALEY, J. C</creatorcontrib><creatorcontrib>FREEMAN, G. M</creatorcontrib><creatorcontrib>FONSECA, A</creatorcontrib><creatorcontrib>INGERSOLL, E. B</creatorcontrib><creatorcontrib>BECKMAN, A. L</creatorcontrib><creatorcontrib>BUNNELL, W. P</creatorcontrib><title>The somatosensory evoked potential predicts neurologic deficits and serotonergic pathochemistry after spinal distraction injury in experimental scoliosis</title><title>Journal of neurotrauma</title><addtitle>J Neurotrauma</addtitle><description>The validity of the somatosensory evoked potential as an intraoperative spinal cord monitor was evaluated in an experimental model of scoliosis in the rat and a Harrington distraction model of injury. Under these conditions, it was found that any change in latency or amplitude of the major negative wave above a certain level was a significant predictor of an adverse neurologic outcome. Changes in latency of 4% or greater and changes in amplitude of 50% or greater were unequivocal indicators of spinal cord injury. Postmortem analyses of the spinal neurotransmitter serotonin revealed that apparent false-positive results of the SEP were, in fact, true-positive results.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Disease Models, Animal</subject><subject>Evoked Potentials, Somatosensory</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Nervous System Diseases - etiology</subject><subject>Nervous System Diseases - metabolism</subject><subject>Nervous System Diseases - physiopathology</subject><subject>Orthopedic surgery</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>Reaction Time</subject><subject>Scoliosis - complications</subject><subject>Scoliosis - metabolism</subject><subject>Scoliosis - physiopathology</subject><subject>Serotonin - metabolism</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><issn>0897-7151</issn><issn>1557-9042</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kUFv1DAQha0KVLaFa29IPiBuCbEd28kRVQUqVeJSzpZjT7ouWTt4HER_Cv-2XnXV00jzvnkzmkfIFeta1g3jlwhby8ZhaGXLtDgjOyalbsau52_IrgK60Uyyd-QC8bHrmFBcn5NzwXulRr4j_-_3QDEdbEkIEVN-ovA3_QZP11QglmAXumbwwRWkdVdOS3oIjnqYgwu1Z6OnCDmVFCEfldWWfXJ7OAQs1c3OBTLFNcTq5I8960pIkYb4uFU9RAr_VsjhULdVBF1aQsKA78nb2S4IH071kvz6dnN__aO5-_n99vrrXeO46Etjh8nakYNmGrgeps47x72GaVC-75VQXklntR-nHqRUSnoteit4BSY_OS8uyecX3zWnPxtgMfVyB8tiI6QNjR50z8XYVbB9AV1OiBlms9arbX4yrDPHLEz9jzlmYaSpWdSBjyfnbTqAf8VPz6_6p5Nu0dllzja6gK-YGoTSNbFnImuY2w</recordid><startdate>1988</startdate><enddate>1988</enddate><creator>SALZMAN, S. K</creator><creator>DABNEY, K. W</creator><creator>MENDEZ, A. A</creator><creator>BEAUCHAMP, J. T</creator><creator>DALEY, J. C</creator><creator>FREEMAN, G. M</creator><creator>FONSECA, A</creator><creator>INGERSOLL, E. B</creator><creator>BECKMAN, A. L</creator><creator>BUNNELL, W. P</creator><general>Liebert</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1988</creationdate><title>The somatosensory evoked potential predicts neurologic deficits and serotonergic pathochemistry after spinal distraction injury in experimental scoliosis</title><author>SALZMAN, S. K ; DABNEY, K. W ; MENDEZ, A. A ; BEAUCHAMP, J. T ; DALEY, J. C ; FREEMAN, G. M ; FONSECA, A ; INGERSOLL, E. B ; BECKMAN, A. L ; BUNNELL, W. P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c234t-a8baa92e717e278b0dcc2d7eb86d44636d65ca7d9b4e55665d734a32eb8bdbcd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Disease Models, Animal</topic><topic>Evoked Potentials, Somatosensory</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Nervous System Diseases - etiology</topic><topic>Nervous System Diseases - metabolism</topic><topic>Nervous System Diseases - physiopathology</topic><topic>Orthopedic surgery</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Reaction Time</topic><topic>Scoliosis - complications</topic><topic>Scoliosis - metabolism</topic><topic>Scoliosis - physiopathology</topic><topic>Serotonin - metabolism</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SALZMAN, S. K</creatorcontrib><creatorcontrib>DABNEY, K. W</creatorcontrib><creatorcontrib>MENDEZ, A. A</creatorcontrib><creatorcontrib>BEAUCHAMP, J. T</creatorcontrib><creatorcontrib>DALEY, J. C</creatorcontrib><creatorcontrib>FREEMAN, G. M</creatorcontrib><creatorcontrib>FONSECA, A</creatorcontrib><creatorcontrib>INGERSOLL, E. B</creatorcontrib><creatorcontrib>BECKMAN, A. L</creatorcontrib><creatorcontrib>BUNNELL, W. P</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of neurotrauma</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SALZMAN, S. K</au><au>DABNEY, K. W</au><au>MENDEZ, A. A</au><au>BEAUCHAMP, J. T</au><au>DALEY, J. C</au><au>FREEMAN, G. M</au><au>FONSECA, A</au><au>INGERSOLL, E. B</au><au>BECKMAN, A. L</au><au>BUNNELL, W. P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The somatosensory evoked potential predicts neurologic deficits and serotonergic pathochemistry after spinal distraction injury in experimental scoliosis</atitle><jtitle>Journal of neurotrauma</jtitle><addtitle>J Neurotrauma</addtitle><date>1988</date><risdate>1988</risdate><volume>5</volume><issue>3</issue><spage>173</spage><epage>186</epage><pages>173-186</pages><issn>0897-7151</issn><eissn>1557-9042</eissn><coden>JNEUE4</coden><abstract>The validity of the somatosensory evoked potential as an intraoperative spinal cord monitor was evaluated in an experimental model of scoliosis in the rat and a Harrington distraction model of injury. Under these conditions, it was found that any change in latency or amplitude of the major negative wave above a certain level was a significant predictor of an adverse neurologic outcome. Changes in latency of 4% or greater and changes in amplitude of 50% or greater were unequivocal indicators of spinal cord injury. Postmortem analyses of the spinal neurotransmitter serotonin revealed that apparent false-positive results of the SEP were, in fact, true-positive results.</abstract><cop>Larchmont, NY</cop><pub>Liebert</pub><pmid>3246692</pmid><doi>10.1089/neu.1988.5.173</doi><tpages>14</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0897-7151 |
| ispartof | Journal of neurotrauma, 1988, Vol.5 (3), p.173-186 |
| issn | 0897-7151 1557-9042 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78742390 |
| source | Mary Ann Liebert Online Subscription; MEDLINE |
| subjects | Animals Biological and medical sciences Disease Models, Animal Evoked Potentials, Somatosensory Male Medical sciences Nervous System Diseases - etiology Nervous System Diseases - metabolism Nervous System Diseases - physiopathology Orthopedic surgery Rats Rats, Inbred Strains Reaction Time Scoliosis - complications Scoliosis - metabolism Scoliosis - physiopathology Serotonin - metabolism Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases |
| title | The somatosensory evoked potential predicts neurologic deficits and serotonergic pathochemistry after spinal distraction injury in experimental scoliosis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T14%3A16%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20somatosensory%20evoked%20potential%20predicts%20neurologic%20deficits%20and%20serotonergic%20pathochemistry%20after%20spinal%20distraction%20injury%20in%20experimental%20scoliosis&rft.jtitle=Journal%20of%20neurotrauma&rft.au=SALZMAN,%20S.%20K&rft.date=1988&rft.volume=5&rft.issue=3&rft.spage=173&rft.epage=186&rft.pages=173-186&rft.issn=0897-7151&rft.eissn=1557-9042&rft.coden=JNEUE4&rft_id=info:doi/10.1089/neu.1988.5.173&rft_dat=%3Cproquest_cross%3E78742390%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=78742390&rft_id=info:pmid/3246692&rfr_iscdi=true |