Effect of GABAergic transmission in the subpallidal region on the hypermotility response to the administration of excitatory amino acids and picrotoxin into the nucleus accumbens

Excitatory amino acids and picrotoxin have been shown to produce an intense stimulation of co-ordinated locomotor activity after bilateral administration into the nucleus accumbens of rats. The objective of this study was to determine the role of GABAergic neurotransmission in the substantia innomin...

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Veröffentlicht in:	Neuropharmacology 1988-12, Vol.27 (12), p.1271-1277
Hauptverfasser:	Shreve, P.E., Uretsky, N.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Amphetamine - pharmacology Animals Aspartic Acid - analogs & derivatives Aspartic Acid - pharmacology Basal Ganglia - drug effects Brain - anatomy & histology excitatory amino acids GABA gamma-Aminobutyric Acid - physiology Ibotenic Acid - analogs & derivatives Ibotenic Acid - pharmacology Kainic Acid - pharmacology lateral preoptic area locomotor activity Male Motor Activity - drug effects Muscimol - pharmacology N-Methylaspartate nucleus accumbens Nucleus Accumbens - drug effects Picrotoxin - pharmacology Rats Rats, Inbred Strains Septal Nuclei - drug effects substantia innominata Substantia Innominata - drug effects Synaptic Transmission - drug effects
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