Treatment of Vancomycin-Resistant Enterococcus faecium Infections With an Investigational Streptogramin Antibiotic (Quinupristin/Dalfopristin): A Report of Fifteen Cases

New therapies for vancomycin-resistant Enterococcus faecium (VREF) infections are urgently needed. We describe the treatment of 15 patients with VREF infection with quinupristin/dalfopristin (RP 59500), a new injectable streptogramin antibiotic. Primary infections treated were bacteremia (4), urinar...

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Veröffentlicht in:	Microbial drug resistance (Larchmont, N.Y.) N.Y.), 1996, Vol.2 (4), p.47-413
Hauptverfasser:	Dever, L L, Smith, S M, Dejesus, D, Masurekar, M, Patel, D, Kaminski, Z C, Johanson, Jr, W G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use DNA, Bacterial - analysis DNA, Bacterial - biosynthesis DNA, Bacterial - isolation & purification Drug Resistance, Microbial Electrophoresis, Polyacrylamide Gel Enterococcus faecium Enterococcus faecium - drug effects Female Gram-Negative Bacterial Infections - drug therapy Gram-Negative Bacterial Infections - microbiology Humans Injections, Intravenous Male Microbial Sensitivity Tests Middle Aged Vancomycin - pharmacology Virginiamycin - administration & dosage Virginiamycin - pharmacology Virginiamycin - therapeutic use
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