Treatment strategies for senile dementia: antagonist β-carbolines

An effective pharmacological treatment for senile dementia is not yet available and even the therapeutic potency of muscarinic agonists has been rather disappointing up to now. Different lines of evidence and a hypothesis are presented below suggesting that β-carbolines with antagonist or partial in...

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Veröffentlicht in:	Trends in neurosciences (Regular ed.) 1988, Vol.11 (1), p.13-17
Hauptverfasser:	Sarter, Martin, Schneider, Herbert H., Stephens, David N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carbolines - therapeutic use Dementia - drug therapy Dementia - metabolism Humans Receptors, GABA-A - drug effects Receptors, GABA-A - metabolism
Online-Zugang:	Volltext
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