A Model of Na super(+)/H super(+) Exchanger and Its Central Role in Regulation of pH and Na super(+) in Cardiac Myocytes

A new kinetic model of the Na super(+)/H super(+) exchanger (NHE) was developed by fitting a variety of major experimental findings, such as ion-dependencies, forward/reverse mode, and the turnover rate. The role of NHE in ion homeostasis was examined by implementing the NHE model in a minimum cell...

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Veröffentlicht in:	Biophysical journal 2009-11, Vol.97 (10), p.2674-2683
Hauptverfasser:	Cha, Chae Young, Oka, Chiaki, Earm, Yung E, Wakabayashi, Shigeo, Noma, Akinori
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidification Dissipation Exchange Fittings Homeostasis Ion exchangers Mathematical models Pumps
Online-Zugang:	Volltext
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