Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot–peptide conjugates

Proteases are enzymes that catalyse the breaking of specific peptide bonds in proteins and polypeptides. They are heavily involved in many normal biological processes as well as in diseases, including cancer, stroke and infection. In fact, proteolytic activity is sometimes used as a marker for some...

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Veröffentlicht in:Nature materials 2006-07, Vol.5 (7), p.581-589
Hauptverfasser: Medintz, Igor L., Clapp, Aaron R., Brunel, Florence M., Tiefenbrunn, Theresa, Tetsuo Uyeda, H., Chang, Eddie L., Deschamps, Jeffrey R., Dawson, Philip E., Mattoussi, Hedi
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Sprache:eng
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