Nucleotide sequence and structure of the mouse cytokeratin endoB gene
We report the isolation and nucleotide sequence (7878 bp) of a genomic clone encoding murine cytokeratin EndoB, a type-I intermediate filament protein that is expressed coordinately with EndoA in trophectoderm cells during blastocyst formation. This clone contains the complete endoB gene including t...
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| Veröffentlicht in: | Gene 1988-10, Vol.70 (1), p.85-95 |
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| container_title | Gene |
| container_volume | 70 |
| creator | Yuki, Icliinose Takashi, Morita Fengyun, Zhang Sattaporn, Srimahasongcram Tondella, Maria Lucia C. Midori, Matsumoto Masami, Nozaki Aizo, Matsushiro |
| description | We report the isolation and nucleotide sequence (7878 bp) of a genomic clone encoding murine cytokeratin EndoB, a type-I intermediate filament protein that is expressed coordinately with EndoA in trophectoderm cells during blastocyst formation. This clone contains the complete endoB gene including the 5' upstream and 3' downstream flanking regions. Sequencing analysis reveals the endoB gene consists of seven exons and six introns. Although the positions of the six introns coincide exactly with those of other type-I cytokeratin genes, the endoB gene has lost the seventh intron, which resides in the sequences coding for tail domains of other type-I cytokeratins. The 5' upstream regions of endoA and endoB genes contain homologous sequences around the respective TATA-like boxes, suggesting their involvement in coordinate regulation of their transcription and/or post-transcription. Surprisingly, this clone contains at least four murine B l repetitive sequences. One typical B1 repetitive sequence was recognized in the 5' upstream region, and the other three in the 3' flanking region. |
| doi_str_mv | 10.1016/0378-1119(88)90107-2 |
| format | Article |
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This clone contains the complete endoB gene including the 5' upstream and 3' downstream flanking regions. Sequencing analysis reveals the endoB gene consists of seven exons and six introns. Although the positions of the six introns coincide exactly with those of other type-I cytokeratin genes, the endoB gene has lost the seventh intron, which resides in the sequences coding for tail domains of other type-I cytokeratins. The 5' upstream regions of endoA and endoB genes contain homologous sequences around the respective TATA-like boxes, suggesting their involvement in coordinate regulation of their transcription and/or post-transcription. Surprisingly, this clone contains at least four murine B l repetitive sequences. One typical B1 repetitive sequence was recognized in the 5' upstream region, and the other three in the 3' flanking region.</description><identifier>ISSN: 0378-1119</identifier><identifier>EISSN: 1879-0038</identifier><identifier>DOI: 10.1016/0378-1119(88)90107-2</identifier><identifier>PMID: 2467843</identifier><identifier>CODEN: GENED6</identifier><language>eng</language><publisher>Lausanne: Elsevier B.V</publisher><subject>Animals ; Biological and medical sciences ; Bl repetitive sequence ; DNA - analysis ; DNA, Recombinant ; exon-intron pattern ; Exons ; Fundamental and applied biological sciences. Psychology ; gene family ; gene structure ; Genes ; Genes. Genome ; intermediate filament ; Introns ; Keratins - genetics ; Mice ; Molecular and cellular biology ; Molecular genetics ; Molecular Sequence Data ; mouse embryo ; Pseudogenes ; Recombinant DNA ; Repetitive Sequences, Nucleic Acid ; Restriction Mapping ; Sequence Homology, Nucleic Acid ; teratocarcinoma</subject><ispartof>Gene, 1988-10, Vol.70 (1), p.85-95</ispartof><rights>1988</rights><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c417t-2a0072f80ea9c2a131efc4458ae5a4c2fecce89d4099a9867ca0ed2a23ee9e883</citedby><cites>FETCH-LOGICAL-c417t-2a0072f80ea9c2a131efc4458ae5a4c2fecce89d4099a9867ca0ed2a23ee9e883</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0378-1119(88)90107-2$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7330689$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2467843$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yuki, Icliinose</creatorcontrib><creatorcontrib>Takashi, Morita</creatorcontrib><creatorcontrib>Fengyun, Zhang</creatorcontrib><creatorcontrib>Sattaporn, Srimahasongcram</creatorcontrib><creatorcontrib>Tondella, Maria Lucia C.</creatorcontrib><creatorcontrib>Midori, Matsumoto</creatorcontrib><creatorcontrib>Masami, Nozaki</creatorcontrib><creatorcontrib>Aizo, Matsushiro</creatorcontrib><title>Nucleotide sequence and structure of the mouse cytokeratin endoB gene</title><title>Gene</title><addtitle>Gene</addtitle><description>We report the isolation and nucleotide sequence (7878 bp) of a genomic clone encoding murine cytokeratin EndoB, a type-I intermediate filament protein that is expressed coordinately with EndoA in trophectoderm cells during blastocyst formation. This clone contains the complete endoB gene including the 5' upstream and 3' downstream flanking regions. Sequencing analysis reveals the endoB gene consists of seven exons and six introns. Although the positions of the six introns coincide exactly with those of other type-I cytokeratin genes, the endoB gene has lost the seventh intron, which resides in the sequences coding for tail domains of other type-I cytokeratins. The 5' upstream regions of endoA and endoB genes contain homologous sequences around the respective TATA-like boxes, suggesting their involvement in coordinate regulation of their transcription and/or post-transcription. Surprisingly, this clone contains at least four murine B l repetitive sequences. One typical B1 repetitive sequence was recognized in the 5' upstream region, and the other three in the 3' flanking region.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Bl repetitive sequence</subject><subject>DNA - analysis</subject><subject>DNA, Recombinant</subject><subject>exon-intron pattern</subject><subject>Exons</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>gene family</subject><subject>gene structure</subject><subject>Genes</subject><subject>Genes. Genome</subject><subject>intermediate filament</subject><subject>Introns</subject><subject>Keratins - genetics</subject><subject>Mice</subject><subject>Molecular and cellular biology</subject><subject>Molecular genetics</subject><subject>Molecular Sequence Data</subject><subject>mouse embryo</subject><subject>Pseudogenes</subject><subject>Recombinant DNA</subject><subject>Repetitive Sequences, Nucleic Acid</subject><subject>Restriction Mapping</subject><subject>Sequence Homology, Nucleic Acid</subject><subject>teratocarcinoma</subject><issn>0378-1119</issn><issn>1879-0038</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1LxDAQhoMoun78A4UcRPRQTdK0SS6Cil8getFziNOpRrutJqngvzfrLnvUucxhnhleniFkl7Njznh9wkqlC865OdT6yDDOVCFWyIRrZQrGSr1KJktkg2zG-MZyVZVYJ-tC1krLckIu70focEi-QRrxc8QekLq-oTGFEdIYkA4tTa9Ip8MYkcJ3Gt4xuOR7in0znNMX7HGbrLWui7iz6Fvk6ery8eKmuHu4vr04uytAcpUK4RhTotUMnQHheMmxBSkr7bByEkSLAKhNI5kxzuhagWPYCCdKRINal1vkYH73Iww5a0x26iNg17keczyrtBJcyP9BXrEsgNcZlHMQwhBjwNZ-BD914dtyZmea7cyhnTm0WttfzVbktb3F_fF5is1yaeE1z_cXcxfBdW1wPfi4xFRZslqbjJ3OMczSvjwGG8HPXtD4gJBsM_i_c_wAH5GYzg</recordid><startdate>19881015</startdate><enddate>19881015</enddate><creator>Yuki, Icliinose</creator><creator>Takashi, Morita</creator><creator>Fengyun, Zhang</creator><creator>Sattaporn, Srimahasongcram</creator><creator>Tondella, Maria Lucia C.</creator><creator>Midori, Matsumoto</creator><creator>Masami, Nozaki</creator><creator>Aizo, Matsushiro</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TM</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>19881015</creationdate><title>Nucleotide sequence and structure of the mouse cytokeratin endoB gene</title><author>Yuki, Icliinose ; Takashi, Morita ; Fengyun, Zhang ; Sattaporn, Srimahasongcram ; Tondella, Maria Lucia C. ; Midori, Matsumoto ; Masami, Nozaki ; Aizo, Matsushiro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-2a0072f80ea9c2a131efc4458ae5a4c2fecce89d4099a9867ca0ed2a23ee9e883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Bl repetitive sequence</topic><topic>DNA - analysis</topic><topic>DNA, Recombinant</topic><topic>exon-intron pattern</topic><topic>Exons</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>gene family</topic><topic>gene structure</topic><topic>Genes</topic><topic>Genes. Genome</topic><topic>intermediate filament</topic><topic>Introns</topic><topic>Keratins - genetics</topic><topic>Mice</topic><topic>Molecular and cellular biology</topic><topic>Molecular genetics</topic><topic>Molecular Sequence Data</topic><topic>mouse embryo</topic><topic>Pseudogenes</topic><topic>Recombinant DNA</topic><topic>Repetitive Sequences, Nucleic Acid</topic><topic>Restriction Mapping</topic><topic>Sequence Homology, Nucleic Acid</topic><topic>teratocarcinoma</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yuki, Icliinose</creatorcontrib><creatorcontrib>Takashi, Morita</creatorcontrib><creatorcontrib>Fengyun, Zhang</creatorcontrib><creatorcontrib>Sattaporn, Srimahasongcram</creatorcontrib><creatorcontrib>Tondella, Maria Lucia C.</creatorcontrib><creatorcontrib>Midori, Matsumoto</creatorcontrib><creatorcontrib>Masami, Nozaki</creatorcontrib><creatorcontrib>Aizo, Matsushiro</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Gene</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yuki, Icliinose</au><au>Takashi, Morita</au><au>Fengyun, Zhang</au><au>Sattaporn, Srimahasongcram</au><au>Tondella, Maria Lucia C.</au><au>Midori, Matsumoto</au><au>Masami, Nozaki</au><au>Aizo, Matsushiro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nucleotide sequence and structure of the mouse cytokeratin endoB gene</atitle><jtitle>Gene</jtitle><addtitle>Gene</addtitle><date>1988-10-15</date><risdate>1988</risdate><volume>70</volume><issue>1</issue><spage>85</spage><epage>95</epage><pages>85-95</pages><issn>0378-1119</issn><eissn>1879-0038</eissn><coden>GENED6</coden><abstract>We report the isolation and nucleotide sequence (7878 bp) of a genomic clone encoding murine cytokeratin EndoB, a type-I intermediate filament protein that is expressed coordinately with EndoA in trophectoderm cells during blastocyst formation. This clone contains the complete endoB gene including the 5' upstream and 3' downstream flanking regions. Sequencing analysis reveals the endoB gene consists of seven exons and six introns. Although the positions of the six introns coincide exactly with those of other type-I cytokeratin genes, the endoB gene has lost the seventh intron, which resides in the sequences coding for tail domains of other type-I cytokeratins. The 5' upstream regions of endoA and endoB genes contain homologous sequences around the respective TATA-like boxes, suggesting their involvement in coordinate regulation of their transcription and/or post-transcription. Surprisingly, this clone contains at least four murine B l repetitive sequences. One typical B1 repetitive sequence was recognized in the 5' upstream region, and the other three in the 3' flanking region.</abstract><cop>Lausanne</cop><cop>Amsterdam</cop><cop>New York, NY</cop><pub>Elsevier B.V</pub><pmid>2467843</pmid><doi>10.1016/0378-1119(88)90107-2</doi><tpages>11</tpages></addata></record> |
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| subjects | Animals Biological and medical sciences Bl repetitive sequence DNA - analysis DNA, Recombinant exon-intron pattern Exons Fundamental and applied biological sciences. Psychology gene family gene structure Genes Genes. Genome intermediate filament Introns Keratins - genetics Mice Molecular and cellular biology Molecular genetics Molecular Sequence Data mouse embryo Pseudogenes Recombinant DNA Repetitive Sequences, Nucleic Acid Restriction Mapping Sequence Homology, Nucleic Acid teratocarcinoma |
| title | Nucleotide sequence and structure of the mouse cytokeratin endoB gene |
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