Correlation of presentation of insulin with surface I-Ad and A alpha and A beta mRNA expression by cloned B lymphoma hybridoma variants

We investigated the relationship between Ia expression and antigen presentation in cloned B cells, using variants of TA3 antigen presenting cells. Two TA3 subclones were selected as high presenters and 5 as low presenters of insulin to pork insulin/I-Ad restricted T cells. All TA3 subclones express...

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Veröffentlicht in:	Immunology letters 1988-10, Vol.19 (2), p.143-151
Hauptverfasser:	Bernard, N F, Reid, P C, Phillips, M L, Delovitch, T L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen-Presenting Cells - immunology B-Lymphocytes - immunology Clone Cells - immunology Gene Expression Regulation Genes, MHC Class II Histocompatibility Antigens Class II - genetics Hybridomas - immunology Insulin - immunology Lymphoma - genetics Lymphoma - immunology RNA, Messenger - genetics Transcription, Genetic
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