Global distribution of ciguatera causing dinoflagellates in the genus Gambierdiscus
Dinoflagellates in the genus Gambierdiscus produce toxins that bioaccumulate in tropical and sub-tropical fishes causing ciguatera fish poisoning (CFP). Little is known about the diversity and distribution of Gambierdiscus species, the degree to which individual species vary in toxicity, and the rol...
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| Veröffentlicht in: | Toxicon (Oxford) 2010-10, Vol.56 (5), p.711-730 |
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| creator | Litaker, R. Wayne Vandersea, Mark W. Faust, Maria A. Kibler, Steven R. Nau, Amy W. Holland, William C. Chinain, Mireille Holmes, Michael J. Tester, Patricia A. |
| description | Dinoflagellates in the genus
Gambierdiscus produce toxins that bioaccumulate in tropical and sub-tropical fishes causing ciguatera fish poisoning (CFP). Little is known about the diversity and distribution of
Gambierdiscus species, the degree to which individual species vary in toxicity, and the role each plays in causing CFP. This paper presents the first global distribution of
Gambierdiscus species. Phylogenetic analyses of the existing isolates indicate that five species are endemic to the Atlantic (including the Caribbean/West Indies and Gulf of Mexico), five are endemic to the tropical Pacific, and that two species,
Gambierdiscus carpenteri and
Gambierdiscus caribaeus are globally distributed. The differences in
Gambierdiscus species composition in the Atlantic and Pacific correlated with structural differences in the ciguatoxins reported from Atlantic and Pacific fish. This correlation supports the hypothesis that
Gambierdiscus species in each region produce different toxin suites. A literature survey indicated a >100-fold variation in toxicity among species compared with a 2 to 9-fold within species variation due to changing growth conditions. These observations suggest that CFP events are driven more by inherent differences in species toxicity than by environmental modulation. How variations in species toxicity may affect the development of an early warning system for CFP is discussed. |
| doi_str_mv | 10.1016/j.toxicon.2010.05.017 |
| format | Article |
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Gambierdiscus produce toxins that bioaccumulate in tropical and sub-tropical fishes causing ciguatera fish poisoning (CFP). Little is known about the diversity and distribution of
Gambierdiscus species, the degree to which individual species vary in toxicity, and the role each plays in causing CFP. This paper presents the first global distribution of
Gambierdiscus species. Phylogenetic analyses of the existing isolates indicate that five species are endemic to the Atlantic (including the Caribbean/West Indies and Gulf of Mexico), five are endemic to the tropical Pacific, and that two species,
Gambierdiscus carpenteri and
Gambierdiscus caribaeus are globally distributed. The differences in
Gambierdiscus species composition in the Atlantic and Pacific correlated with structural differences in the ciguatoxins reported from Atlantic and Pacific fish. This correlation supports the hypothesis that
Gambierdiscus species in each region produce different toxin suites. A literature survey indicated a >100-fold variation in toxicity among species compared with a 2 to 9-fold within species variation due to changing growth conditions. These observations suggest that CFP events are driven more by inherent differences in species toxicity than by environmental modulation. How variations in species toxicity may affect the development of an early warning system for CFP is discussed.</description><identifier>ISSN: 0041-0101</identifier><identifier>EISSN: 1879-3150</identifier><identifier>DOI: 10.1016/j.toxicon.2010.05.017</identifier><identifier>PMID: 20561539</identifier><identifier>CODEN: TOXIA6</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Animal poisons toxicology. Antivenoms ; Biogeography ; Biological and medical sciences ; CFP ; Ciguatera fish poisoning ; Ciguatera Poisoning - chemically induced ; Ciguatoxins - toxicity ; Correlation ; Dinoflagellates ; Dinoflagellida - classification ; Dinoflagellida - pathogenicity ; Early warning systems ; Fish ; G. belizeanus ; G. caribaeus ; G. carolinianus ; G. carpenteri ; G. pacificus ; G. polynesiensis ; G. ruetzleri ; G. toxicus ; G. yasumotoi ; Gambierdiscus australes ; Gulf of Mexico ; Maitotoxin ; Medical sciences ; Modulation ; Monitoring ; Phylogeny ; Plant poisons toxicology ; Ribotype ; Species Specificity ; Toxicity ; Toxicology ; Toxins ; West Indies</subject><ispartof>Toxicon (Oxford), 2010-10, Vol.56 (5), p.711-730</ispartof><rights>2010</rights><rights>2015 INIST-CNRS</rights><rights>Published by Elsevier Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c492t-a61012b81303a8f548236d5f4308ee07aab1618957355be4f91a9b8889bdb6ca3</citedby><cites>FETCH-LOGICAL-c492t-a61012b81303a8f548236d5f4308ee07aab1618957355be4f91a9b8889bdb6ca3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S004101011000214X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>309,310,314,776,780,785,786,3537,23909,23910,25118,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23259049$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20561539$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Litaker, R. Wayne</creatorcontrib><creatorcontrib>Vandersea, Mark W.</creatorcontrib><creatorcontrib>Faust, Maria A.</creatorcontrib><creatorcontrib>Kibler, Steven R.</creatorcontrib><creatorcontrib>Nau, Amy W.</creatorcontrib><creatorcontrib>Holland, William C.</creatorcontrib><creatorcontrib>Chinain, Mireille</creatorcontrib><creatorcontrib>Holmes, Michael J.</creatorcontrib><creatorcontrib>Tester, Patricia A.</creatorcontrib><title>Global distribution of ciguatera causing dinoflagellates in the genus Gambierdiscus</title><title>Toxicon (Oxford)</title><addtitle>Toxicon</addtitle><description>Dinoflagellates in the genus
Gambierdiscus produce toxins that bioaccumulate in tropical and sub-tropical fishes causing ciguatera fish poisoning (CFP). Little is known about the diversity and distribution of
Gambierdiscus species, the degree to which individual species vary in toxicity, and the role each plays in causing CFP. This paper presents the first global distribution of
Gambierdiscus species. Phylogenetic analyses of the existing isolates indicate that five species are endemic to the Atlantic (including the Caribbean/West Indies and Gulf of Mexico), five are endemic to the tropical Pacific, and that two species,
Gambierdiscus carpenteri and
Gambierdiscus caribaeus are globally distributed. The differences in
Gambierdiscus species composition in the Atlantic and Pacific correlated with structural differences in the ciguatoxins reported from Atlantic and Pacific fish. This correlation supports the hypothesis that
Gambierdiscus species in each region produce different toxin suites. A literature survey indicated a >100-fold variation in toxicity among species compared with a 2 to 9-fold within species variation due to changing growth conditions. These observations suggest that CFP events are driven more by inherent differences in species toxicity than by environmental modulation. How variations in species toxicity may affect the development of an early warning system for CFP is discussed.</description><subject>Animal poisons toxicology. Antivenoms</subject><subject>Biogeography</subject><subject>Biological and medical sciences</subject><subject>CFP</subject><subject>Ciguatera fish poisoning</subject><subject>Ciguatera Poisoning - chemically induced</subject><subject>Ciguatoxins - toxicity</subject><subject>Correlation</subject><subject>Dinoflagellates</subject><subject>Dinoflagellida - classification</subject><subject>Dinoflagellida - pathogenicity</subject><subject>Early warning systems</subject><subject>Fish</subject><subject>G. belizeanus</subject><subject>G. caribaeus</subject><subject>G. carolinianus</subject><subject>G. carpenteri</subject><subject>G. pacificus</subject><subject>G. polynesiensis</subject><subject>G. ruetzleri</subject><subject>G. toxicus</subject><subject>G. yasumotoi</subject><subject>Gambierdiscus australes</subject><subject>Gulf of Mexico</subject><subject>Maitotoxin</subject><subject>Medical sciences</subject><subject>Modulation</subject><subject>Monitoring</subject><subject>Phylogeny</subject><subject>Plant poisons toxicology</subject><subject>Ribotype</subject><subject>Species Specificity</subject><subject>Toxicity</subject><subject>Toxicology</subject><subject>Toxins</subject><subject>West Indies</subject><issn>0041-0101</issn><issn>1879-3150</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMFu1DAQhi1ERbeFRwDlgnrKdhzHiX1CqKLbSpU4UM7W2JksXmXtYicI3r5e7QLHnkaa-Wbm18fYew5rDry73q3n-Nu7GNYNlB7INfD-FVtx1etacAmv2Qqg5XWZ8nN2kfMOAITS3Rt23oDsuBR6xb5tpmhxqgaf5-TtMvsYqjhWzm8XnClh5XDJPmwLEeI44ZamqQxy5UM1_6BqS2HJ1Qb31lMqV9yS37KzEadM7071kn2__fJ4c1c_fN3c33x-qF2rm7nGriRrrOICBKpRtqoR3SDHVoAigh7R8o4rLXshpaV21By1VUppO9jOobhkV8e7Tyn-XCjPZl_-H_IFiks2veo5qLaRhZRH0qWYc6LRPCW_x_THcDAHnWZnTjrNQacBaYrOsvfh9GGxexr-bf31V4CPJwCzw2lMGJzP_znRSA3tgft05Kj4-FVMmew8BUeDT-RmM0T_QpRnNaKWWA</recordid><startdate>20101001</startdate><enddate>20101001</enddate><creator>Litaker, R. Wayne</creator><creator>Vandersea, Mark W.</creator><creator>Faust, Maria A.</creator><creator>Kibler, Steven R.</creator><creator>Nau, Amy W.</creator><creator>Holland, William C.</creator><creator>Chinain, Mireille</creator><creator>Holmes, Michael J.</creator><creator>Tester, Patricia A.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>KR7</scope></search><sort><creationdate>20101001</creationdate><title>Global distribution of ciguatera causing dinoflagellates in the genus Gambierdiscus</title><author>Litaker, R. 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Wayne</au><au>Vandersea, Mark W.</au><au>Faust, Maria A.</au><au>Kibler, Steven R.</au><au>Nau, Amy W.</au><au>Holland, William C.</au><au>Chinain, Mireille</au><au>Holmes, Michael J.</au><au>Tester, Patricia A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Global distribution of ciguatera causing dinoflagellates in the genus Gambierdiscus</atitle><jtitle>Toxicon (Oxford)</jtitle><addtitle>Toxicon</addtitle><date>2010-10-01</date><risdate>2010</risdate><volume>56</volume><issue>5</issue><spage>711</spage><epage>730</epage><pages>711-730</pages><issn>0041-0101</issn><eissn>1879-3150</eissn><coden>TOXIA6</coden><abstract>Dinoflagellates in the genus
Gambierdiscus produce toxins that bioaccumulate in tropical and sub-tropical fishes causing ciguatera fish poisoning (CFP). Little is known about the diversity and distribution of
Gambierdiscus species, the degree to which individual species vary in toxicity, and the role each plays in causing CFP. This paper presents the first global distribution of
Gambierdiscus species. Phylogenetic analyses of the existing isolates indicate that five species are endemic to the Atlantic (including the Caribbean/West Indies and Gulf of Mexico), five are endemic to the tropical Pacific, and that two species,
Gambierdiscus carpenteri and
Gambierdiscus caribaeus are globally distributed. The differences in
Gambierdiscus species composition in the Atlantic and Pacific correlated with structural differences in the ciguatoxins reported from Atlantic and Pacific fish. This correlation supports the hypothesis that
Gambierdiscus species in each region produce different toxin suites. A literature survey indicated a >100-fold variation in toxicity among species compared with a 2 to 9-fold within species variation due to changing growth conditions. These observations suggest that CFP events are driven more by inherent differences in species toxicity than by environmental modulation. How variations in species toxicity may affect the development of an early warning system for CFP is discussed.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>20561539</pmid><doi>10.1016/j.toxicon.2010.05.017</doi><tpages>20</tpages></addata></record> |
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| subjects | Animal poisons toxicology. Antivenoms Biogeography Biological and medical sciences CFP Ciguatera fish poisoning Ciguatera Poisoning - chemically induced Ciguatoxins - toxicity Correlation Dinoflagellates Dinoflagellida - classification Dinoflagellida - pathogenicity Early warning systems Fish G. belizeanus G. caribaeus G. carolinianus G. carpenteri G. pacificus G. polynesiensis G. ruetzleri G. toxicus G. yasumotoi Gambierdiscus australes Gulf of Mexico Maitotoxin Medical sciences Modulation Monitoring Phylogeny Plant poisons toxicology Ribotype Species Specificity Toxicity Toxicology Toxins West Indies |
| title | Global distribution of ciguatera causing dinoflagellates in the genus Gambierdiscus |
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