Complement levels in dogs with familial canine dermatomyositis
CH 50, C4, C2, and C3 levels were evaluated in 7 dogs affected with dermatomyositis and in 22 control dogs. Dogs with dermatomyositis did not have clinical evidence of active disease at the time of serum collection for complement assays. No absolute complement component deficiency was identified in...
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Veröffentlicht in: | Veterinary immunology and immunopathology 1988-12, Vol.20 (1), p.95-100 |
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creator | Hargis, Ann.M. Winkelstein, Jerry A. Moore, Michael P. Weidner, Jay P. Prieur, David J. |
description | CH
50, C4, C2, and C3 levels were evaluated in 7 dogs affected with dermatomyositis and in 22 control dogs. Dogs with dermatomyositis did not have clinical evidence of active disease at the time of serum collection for complement assays. No absolute complement component deficiency was identified in dermatomyositis-affected dogs in this study; however, a statistical difference in C2 was identified between control dogs of non-collie breeds and control collies, suggesting there may be a breed difference in complement levels. |
doi_str_mv | 10.1016/0165-2427(88)90029-3 |
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50, C4, C2, and C3 levels were evaluated in 7 dogs affected with dermatomyositis and in 22 control dogs. Dogs with dermatomyositis did not have clinical evidence of active disease at the time of serum collection for complement assays. No absolute complement component deficiency was identified in dermatomyositis-affected dogs in this study; however, a statistical difference in C2 was identified between control dogs of non-collie breeds and control collies, suggesting there may be a breed difference in complement levels.</description><identifier>ISSN: 0165-2427</identifier><identifier>EISSN: 1873-2534</identifier><identifier>DOI: 10.1016/0165-2427(88)90029-3</identifier><identifier>PMID: 3238922</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Animals ; Complement C2 - genetics ; Complement C2 - immunology ; Complement System Proteins - analysis ; Dermatomyositis - genetics ; Dermatomyositis - immunology ; Dermatomyositis - veterinary ; Dog Diseases - immunology ; Dogs - genetics ; Dogs - immunology ; Female ; Male</subject><ispartof>Veterinary immunology and immunopathology, 1988-12, Vol.20 (1), p.95-100</ispartof><rights>1988</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c388t-c5b48d994a755d09d4665bde68a1f9aa8c4404b22cf657a7561b5a79888675b93</citedby><cites>FETCH-LOGICAL-c388t-c5b48d994a755d09d4665bde68a1f9aa8c4404b22cf657a7561b5a79888675b93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0165-2427(88)90029-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27922,27923,45993</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3238922$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hargis, Ann.M.</creatorcontrib><creatorcontrib>Winkelstein, Jerry A.</creatorcontrib><creatorcontrib>Moore, Michael P.</creatorcontrib><creatorcontrib>Weidner, Jay P.</creatorcontrib><creatorcontrib>Prieur, David J.</creatorcontrib><title>Complement levels in dogs with familial canine dermatomyositis</title><title>Veterinary immunology and immunopathology</title><addtitle>Vet Immunol Immunopathol</addtitle><description>CH
50, C4, C2, and C3 levels were evaluated in 7 dogs affected with dermatomyositis and in 22 control dogs. Dogs with dermatomyositis did not have clinical evidence of active disease at the time of serum collection for complement assays. No absolute complement component deficiency was identified in dermatomyositis-affected dogs in this study; however, a statistical difference in C2 was identified between control dogs of non-collie breeds and control collies, suggesting there may be a breed difference in complement levels.</description><subject>Animals</subject><subject>Complement C2 - genetics</subject><subject>Complement C2 - immunology</subject><subject>Complement System Proteins - analysis</subject><subject>Dermatomyositis - genetics</subject><subject>Dermatomyositis - immunology</subject><subject>Dermatomyositis - veterinary</subject><subject>Dog Diseases - immunology</subject><subject>Dogs - genetics</subject><subject>Dogs - immunology</subject><subject>Female</subject><subject>Male</subject><issn>0165-2427</issn><issn>1873-2534</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDtPwzAQgC0EKqXwD0DKhGAI2I7t2EslVPGSKrHAbDn2BYzipMRpUf89Lq06wnC64b57fQidE3xDMBG3KXhOGS2vpLxWGFOVFwdoTGRZ5JQX7BCN98gxOonxE2PMlZQjNCpoIRWlYzSddWHRQIB2yBpYQRMz32aue4_Ztx8-stoE33jTZNa0voXMQR_M0IV1F_3g4yk6qk0T4WyXJ-jt4f519pTPXx6fZ3fz3BZSDrnlFZNOKWZKzh1WjgnBKwdCGlIrY6RlDLOKUlsLXiZIkIqbMt0qRckrVUzQ5Xbuou--lhAHHXy00DSmhW4ZdSlLrGj6_D-QcMIkYyKBbAvavouxh1oveh9Mv9YE641fvZGnN_K0lPrXry5S28Vu_rIK4PZNO6GpPt3Wk0lYeeh1tB5aC873YAftOv_3gh9yUojj</recordid><startdate>19881201</startdate><enddate>19881201</enddate><creator>Hargis, Ann.M.</creator><creator>Winkelstein, Jerry A.</creator><creator>Moore, Michael P.</creator><creator>Weidner, Jay P.</creator><creator>Prieur, David J.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19881201</creationdate><title>Complement levels in dogs with familial canine dermatomyositis</title><author>Hargis, Ann.M. ; Winkelstein, Jerry A. ; Moore, Michael P. ; Weidner, Jay P. ; Prieur, David J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c388t-c5b48d994a755d09d4665bde68a1f9aa8c4404b22cf657a7561b5a79888675b93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Animals</topic><topic>Complement C2 - genetics</topic><topic>Complement C2 - immunology</topic><topic>Complement System Proteins - analysis</topic><topic>Dermatomyositis - genetics</topic><topic>Dermatomyositis - immunology</topic><topic>Dermatomyositis - veterinary</topic><topic>Dog Diseases - immunology</topic><topic>Dogs - genetics</topic><topic>Dogs - immunology</topic><topic>Female</topic><topic>Male</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hargis, Ann.M.</creatorcontrib><creatorcontrib>Winkelstein, Jerry A.</creatorcontrib><creatorcontrib>Moore, Michael P.</creatorcontrib><creatorcontrib>Weidner, Jay P.</creatorcontrib><creatorcontrib>Prieur, David J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Veterinary immunology and immunopathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hargis, Ann.M.</au><au>Winkelstein, Jerry A.</au><au>Moore, Michael P.</au><au>Weidner, Jay P.</au><au>Prieur, David J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Complement levels in dogs with familial canine dermatomyositis</atitle><jtitle>Veterinary immunology and immunopathology</jtitle><addtitle>Vet Immunol Immunopathol</addtitle><date>1988-12-01</date><risdate>1988</risdate><volume>20</volume><issue>1</issue><spage>95</spage><epage>100</epage><pages>95-100</pages><issn>0165-2427</issn><eissn>1873-2534</eissn><abstract>CH
50, C4, C2, and C3 levels were evaluated in 7 dogs affected with dermatomyositis and in 22 control dogs. Dogs with dermatomyositis did not have clinical evidence of active disease at the time of serum collection for complement assays. No absolute complement component deficiency was identified in dermatomyositis-affected dogs in this study; however, a statistical difference in C2 was identified between control dogs of non-collie breeds and control collies, suggesting there may be a breed difference in complement levels.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>3238922</pmid><doi>10.1016/0165-2427(88)90029-3</doi><tpages>6</tpages></addata></record> |
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subjects | Animals Complement C2 - genetics Complement C2 - immunology Complement System Proteins - analysis Dermatomyositis - genetics Dermatomyositis - immunology Dermatomyositis - veterinary Dog Diseases - immunology Dogs - genetics Dogs - immunology Female Male |
title | Complement levels in dogs with familial canine dermatomyositis |
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