Epiblast Stem Cell Subpopulations Represent Mouse Embryos of Distinct Pregastrulation Stages

Embryonic stem cells (ESCs) comprise at least two populations of cells with divergent states of pluripotency. Here, we show that epiblast stem cells (EpiSCs) also comprise two distinct cell populations that can be distinguished by the expression of a specific Oct4-GFP marker. These two subpopulation...

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Veröffentlicht in:	Cell 2010-11, Vol.143 (4), p.617-627
Hauptverfasser:	Han, Dong Wook, Tapia, Natalia, Joo, Jin Young, Greber, Boris, Araúzo-Bravo, Marcos J., Bernemann, Christof, Ko, Kinarm, Wu, Guangming, Stehling, Martin, Do, Jeong Tae, Schöler, Hans R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Female Gene Expression Profiling Germ Layers - cytology Male Mice - embryology Mice, 129 Strain Mice, Inbred C57BL Octamer Transcription Factor-3 - analysis Octamer Transcription Factor-3 - genetics Pluripotent Stem Cells - cytology Pluripotent Stem Cells - metabolism Stem Cells - cytology
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