Various functions of PBMC from colon cancer patients are not decreased compared to healthy blood donors

The immune surveillance hypothesis suggests impaired immune responses to participate in development of cancer. This may partly be due to increased amounts of PGE2 and histamine, which inhibit cellular immunity. These effects are mediated by cAMP, which is increased and thereby may down-regulate IL-2...

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Veröffentlicht in:	Cancer biotherapy & radiopharmaceuticals 1997-04, Vol.12 (2), p.73-78
Hauptverfasser:	AFZELIUS, P, NIELSEN, H. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Colonic Neoplasms - immunology Cyclic AMP - genetics Gastroenterology. Liver. Pancreas. Abdomen Humans Interleukin-2 - genetics Leukocytes, Mononuclear - physiology Medical sciences Receptors, Interleukin-2 - genetics RNA, Messenger - analysis Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors
Online-Zugang:	Volltext
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