PREVALENCE OF NON-ALCOHOLIC FATTY LIVER IN A HYPERCHOLESTEROLEMIC POPULATION OF NORTHWESTERN PENINSULAR MALAYSIA
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and a frequent finding on ultrasound examination. NAFLD is considered as the liver component of metabolic syndrome and is linked to accelerated atherosclerosis and cardiovascular disease. No data from systematic stu...
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Veröffentlicht in: | Southeast Asian journal of tropical medicine and public health 2010-07, Vol.41 (4), p.936-942 |
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creator | MAGOSSO, Enrico MUKHTAR ALAM ANSARI GOPALAN, Yogheswaran MOHAMED RIZAL ABU BAKAR NURZALINA ABDUL KARIM KHAN JIA WOEI WONG BEE HONG NG KAH HAY YUEN IBRAHIM LUTFI SHUAIB NESARETNAM, Kalanithi |
description | Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and a frequent finding on ultrasound examination. NAFLD is considered as the liver component of metabolic syndrome and is linked to accelerated atherosclerosis and cardiovascular disease. No data from systematic studies regarding the prevalence of NAFLD are available for the Malaysian population. One hundred eighty untreated hypercholesterolemic volunteers underwent blood and ultrasound examinations to evaluate their livers. NAFLD was diagnosed in 102 subjects (56.7%) with similar prevalences between sexes. Of the 102 positive subjects 82 (80.4%) were graded as mild, 17 (16.7%) as moderate and 3 (2.9%) as severe fatty liver cases. Elevated fasting plasma glucose (FPG) levels were found in 13 of 180 subjects (7.2%), while elevated AST and ALT levels were seen in 30 (16.7%) and 22 (12.2%) of the180 subjects, respectively. |
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NAFLD is considered as the liver component of metabolic syndrome and is linked to accelerated atherosclerosis and cardiovascular disease. No data from systematic studies regarding the prevalence of NAFLD are available for the Malaysian population. One hundred eighty untreated hypercholesterolemic volunteers underwent blood and ultrasound examinations to evaluate their livers. NAFLD was diagnosed in 102 subjects (56.7%) with similar prevalences between sexes. Of the 102 positive subjects 82 (80.4%) were graded as mild, 17 (16.7%) as moderate and 3 (2.9%) as severe fatty liver cases. Elevated fasting plasma glucose (FPG) levels were found in 13 of 180 subjects (7.2%), while elevated AST and ALT levels were seen in 30 (16.7%) and 22 (12.2%) of the180 subjects, respectively.</description><identifier>ISSN: 0125-1562</identifier><identifier>PMID: 21073069</identifier><identifier>CODEN: SJTMAK</identifier><language>eng</language><publisher>Bangkok: SEAMO, Regional Tropical Medicine and Public Health Network</publisher><subject>Addictive behaviors ; Adult ; Adult and adolescent clinical studies ; Aged ; Alcoholism ; Alcoholism and acute alcohol poisoning ; Biological and medical sciences ; Fatty Liver - complications ; Fatty Liver - diagnostic imaging ; Fatty Liver - epidemiology ; Female ; General aspects ; Humans ; Hypercholesterolemia - complications ; Hypercholesterolemia - epidemiology ; Malaysia - epidemiology ; Male ; Medical sciences ; Middle Aged ; Non-alcoholic Fatty Liver Disease ; Prevalence ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Toxicology ; Ultrasonography</subject><ispartof>Southeast Asian journal of tropical medicine and public health, 2010-07, Vol.41 (4), p.936-942</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright Central Coordinating Board, SEAMEO-TROPMED Project Jul 2010</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23098885$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21073069$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MAGOSSO, Enrico</creatorcontrib><creatorcontrib>MUKHTAR ALAM ANSARI</creatorcontrib><creatorcontrib>GOPALAN, Yogheswaran</creatorcontrib><creatorcontrib>MOHAMED RIZAL ABU BAKAR</creatorcontrib><creatorcontrib>NURZALINA ABDUL KARIM KHAN</creatorcontrib><creatorcontrib>JIA WOEI WONG</creatorcontrib><creatorcontrib>BEE HONG NG</creatorcontrib><creatorcontrib>KAH HAY YUEN</creatorcontrib><creatorcontrib>IBRAHIM LUTFI SHUAIB</creatorcontrib><creatorcontrib>NESARETNAM, Kalanithi</creatorcontrib><title>PREVALENCE OF NON-ALCOHOLIC FATTY LIVER IN A HYPERCHOLESTEROLEMIC POPULATION OF NORTHWESTERN PENINSULAR MALAYSIA</title><title>Southeast Asian journal of tropical medicine and public health</title><addtitle>Southeast Asian J Trop Med Public Health</addtitle><description>Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and a frequent finding on ultrasound examination. NAFLD is considered as the liver component of metabolic syndrome and is linked to accelerated atherosclerosis and cardiovascular disease. No data from systematic studies regarding the prevalence of NAFLD are available for the Malaysian population. One hundred eighty untreated hypercholesterolemic volunteers underwent blood and ultrasound examinations to evaluate their livers. NAFLD was diagnosed in 102 subjects (56.7%) with similar prevalences between sexes. Of the 102 positive subjects 82 (80.4%) were graded as mild, 17 (16.7%) as moderate and 3 (2.9%) as severe fatty liver cases. Elevated fasting plasma glucose (FPG) levels were found in 13 of 180 subjects (7.2%), while elevated AST and ALT levels were seen in 30 (16.7%) and 22 (12.2%) of the180 subjects, respectively.</description><subject>Addictive behaviors</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Aged</subject><subject>Alcoholism</subject><subject>Alcoholism and acute alcohol poisoning</subject><subject>Biological and medical sciences</subject><subject>Fatty Liver - complications</subject><subject>Fatty Liver - diagnostic imaging</subject><subject>Fatty Liver - epidemiology</subject><subject>Female</subject><subject>General aspects</subject><subject>Humans</subject><subject>Hypercholesterolemia - complications</subject><subject>Hypercholesterolemia - epidemiology</subject><subject>Malaysia - epidemiology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Non-alcoholic Fatty Liver Disease</subject><subject>Prevalence</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Toxicology</subject><subject>Ultrasonography</subject><issn>0125-1562</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpd0MtKw0AUBuAsFFurryCDIK4Cc0lmkuUQpiYwnYQ0rXQVJjdoSduYMQvf3sFWBDmLs_g_fg7nxplDhH0X-RTPnHtjDhB6EIXBnTPDCDICaTh3hiwXWy6FigRIl0ClyuUySuNUJhFY8qLYAZlsRQ4SBTiId5nIIxuKdSFyu1ZWZWm2kbxIUnVpyIv4_SdXIBMqUWub5mDFJd-tE_7g3Ha6N-3jdS-czVIUUezK9C2JuHQHTNmn64W0orAKGIQtgmGnYaNxgGq_Jk3TBpoEfmOHYZ8iRgmtq6YJYYchrlHFKp8snNdL7zCeP6bWfJbHvanbvten9jyZktlqD5KQWPn8Tx7O03iyx5XMo4wxFGKLnq5oqo5tUw7j_qjHr_L3kxa8XIE2te67UZ_qvflzBIZBEPjkGzSFcPE</recordid><startdate>20100701</startdate><enddate>20100701</enddate><creator>MAGOSSO, Enrico</creator><creator>MUKHTAR ALAM ANSARI</creator><creator>GOPALAN, Yogheswaran</creator><creator>MOHAMED RIZAL ABU BAKAR</creator><creator>NURZALINA ABDUL KARIM KHAN</creator><creator>JIA WOEI WONG</creator><creator>BEE HONG NG</creator><creator>KAH HAY YUEN</creator><creator>IBRAHIM LUTFI SHUAIB</creator><creator>NESARETNAM, Kalanithi</creator><general>SEAMO, Regional Tropical Medicine and Public Health Network</general><general>Central Coordinating Board, SEAMEO-TROPMED Project</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7QL</scope><scope>7SS</scope><scope>7T7</scope><scope>7U7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BVBZV</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>P64</scope><scope>PATMY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PYCSY</scope><scope>7X8</scope></search><sort><creationdate>20100701</creationdate><title>PREVALENCE OF NON-ALCOHOLIC FATTY LIVER IN A HYPERCHOLESTEROLEMIC POPULATION OF NORTHWESTERN PENINSULAR MALAYSIA</title><author>MAGOSSO, Enrico ; MUKHTAR ALAM ANSARI ; GOPALAN, Yogheswaran ; MOHAMED RIZAL ABU BAKAR ; NURZALINA ABDUL KARIM KHAN ; JIA WOEI WONG ; BEE HONG NG ; KAH HAY YUEN ; IBRAHIM LUTFI SHUAIB ; NESARETNAM, Kalanithi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p267t-496b60b8700e109fa0da281c5c3dde8a385d5d5725617636cbdd90f202c1b7b53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Addictive behaviors</topic><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Aged</topic><topic>Alcoholism</topic><topic>Alcoholism and acute alcohol poisoning</topic><topic>Biological and medical sciences</topic><topic>Fatty Liver - complications</topic><topic>Fatty Liver - diagnostic imaging</topic><topic>Fatty Liver - epidemiology</topic><topic>Female</topic><topic>General aspects</topic><topic>Humans</topic><topic>Hypercholesterolemia - complications</topic><topic>Hypercholesterolemia - epidemiology</topic><topic>Malaysia - epidemiology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Non-alcoholic Fatty Liver Disease</topic><topic>Prevalence</topic><topic>Psychology. 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NAFLD is considered as the liver component of metabolic syndrome and is linked to accelerated atherosclerosis and cardiovascular disease. No data from systematic studies regarding the prevalence of NAFLD are available for the Malaysian population. One hundred eighty untreated hypercholesterolemic volunteers underwent blood and ultrasound examinations to evaluate their livers. NAFLD was diagnosed in 102 subjects (56.7%) with similar prevalences between sexes. Of the 102 positive subjects 82 (80.4%) were graded as mild, 17 (16.7%) as moderate and 3 (2.9%) as severe fatty liver cases. Elevated fasting plasma glucose (FPG) levels were found in 13 of 180 subjects (7.2%), while elevated AST and ALT levels were seen in 30 (16.7%) and 22 (12.2%) of the180 subjects, respectively.</abstract><cop>Bangkok</cop><pub>SEAMO, Regional Tropical Medicine and Public Health Network</pub><pmid>21073069</pmid><tpages>7</tpages></addata></record> |
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subjects | Addictive behaviors Adult Adult and adolescent clinical studies Aged Alcoholism Alcoholism and acute alcohol poisoning Biological and medical sciences Fatty Liver - complications Fatty Liver - diagnostic imaging Fatty Liver - epidemiology Female General aspects Humans Hypercholesterolemia - complications Hypercholesterolemia - epidemiology Malaysia - epidemiology Male Medical sciences Middle Aged Non-alcoholic Fatty Liver Disease Prevalence Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Toxicology Ultrasonography |
title | PREVALENCE OF NON-ALCOHOLIC FATTY LIVER IN A HYPERCHOLESTEROLEMIC POPULATION OF NORTHWESTERN PENINSULAR MALAYSIA |
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