PREVALENCE OF NON-ALCOHOLIC FATTY LIVER IN A HYPERCHOLESTEROLEMIC POPULATION OF NORTHWESTERN PENINSULAR MALAYSIA

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and a frequent finding on ultrasound examination. NAFLD is considered as the liver component of metabolic syndrome and is linked to accelerated atherosclerosis and cardiovascular disease. No data from systematic stu...

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Veröffentlicht in:Southeast Asian journal of tropical medicine and public health 2010-07, Vol.41 (4), p.936-942
Hauptverfasser: MAGOSSO, Enrico, MUKHTAR ALAM ANSARI, GOPALAN, Yogheswaran, MOHAMED RIZAL ABU BAKAR, NURZALINA ABDUL KARIM KHAN, JIA WOEI WONG, BEE HONG NG, KAH HAY YUEN, IBRAHIM LUTFI SHUAIB, NESARETNAM, Kalanithi
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container_issue 4
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container_title Southeast Asian journal of tropical medicine and public health
container_volume 41
creator MAGOSSO, Enrico
MUKHTAR ALAM ANSARI
GOPALAN, Yogheswaran
MOHAMED RIZAL ABU BAKAR
NURZALINA ABDUL KARIM KHAN
JIA WOEI WONG
BEE HONG NG
KAH HAY YUEN
IBRAHIM LUTFI SHUAIB
NESARETNAM, Kalanithi
description Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and a frequent finding on ultrasound examination. NAFLD is considered as the liver component of metabolic syndrome and is linked to accelerated atherosclerosis and cardiovascular disease. No data from systematic studies regarding the prevalence of NAFLD are available for the Malaysian population. One hundred eighty untreated hypercholesterolemic volunteers underwent blood and ultrasound examinations to evaluate their livers. NAFLD was diagnosed in 102 subjects (56.7%) with similar prevalences between sexes. Of the 102 positive subjects 82 (80.4%) were graded as mild, 17 (16.7%) as moderate and 3 (2.9%) as severe fatty liver cases. Elevated fasting plasma glucose (FPG) levels were found in 13 of 180 subjects (7.2%), while elevated AST and ALT levels were seen in 30 (16.7%) and 22 (12.2%) of the180 subjects, respectively.
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NAFLD is considered as the liver component of metabolic syndrome and is linked to accelerated atherosclerosis and cardiovascular disease. No data from systematic studies regarding the prevalence of NAFLD are available for the Malaysian population. One hundred eighty untreated hypercholesterolemic volunteers underwent blood and ultrasound examinations to evaluate their livers. NAFLD was diagnosed in 102 subjects (56.7%) with similar prevalences between sexes. Of the 102 positive subjects 82 (80.4%) were graded as mild, 17 (16.7%) as moderate and 3 (2.9%) as severe fatty liver cases. 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NAFLD is considered as the liver component of metabolic syndrome and is linked to accelerated atherosclerosis and cardiovascular disease. No data from systematic studies regarding the prevalence of NAFLD are available for the Malaysian population. One hundred eighty untreated hypercholesterolemic volunteers underwent blood and ultrasound examinations to evaluate their livers. NAFLD was diagnosed in 102 subjects (56.7%) with similar prevalences between sexes. Of the 102 positive subjects 82 (80.4%) were graded as mild, 17 (16.7%) as moderate and 3 (2.9%) as severe fatty liver cases. Elevated fasting plasma glucose (FPG) levels were found in 13 of 180 subjects (7.2%), while elevated AST and ALT levels were seen in 30 (16.7%) and 22 (12.2%) of the180 subjects, respectively.</description><subject>Addictive behaviors</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Aged</subject><subject>Alcoholism</subject><subject>Alcoholism and acute alcohol poisoning</subject><subject>Biological and medical sciences</subject><subject>Fatty Liver - complications</subject><subject>Fatty Liver - diagnostic imaging</subject><subject>Fatty Liver - epidemiology</subject><subject>Female</subject><subject>General aspects</subject><subject>Humans</subject><subject>Hypercholesterolemia - complications</subject><subject>Hypercholesterolemia - epidemiology</subject><subject>Malaysia - epidemiology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Non-alcoholic Fatty Liver Disease</subject><subject>Prevalence</subject><subject>Psychology. 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subjects Addictive behaviors
Adult
Adult and adolescent clinical studies
Aged
Alcoholism
Alcoholism and acute alcohol poisoning
Biological and medical sciences
Fatty Liver - complications
Fatty Liver - diagnostic imaging
Fatty Liver - epidemiology
Female
General aspects
Humans
Hypercholesterolemia - complications
Hypercholesterolemia - epidemiology
Malaysia - epidemiology
Male
Medical sciences
Middle Aged
Non-alcoholic Fatty Liver Disease
Prevalence
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Toxicology
Ultrasonography
title PREVALENCE OF NON-ALCOHOLIC FATTY LIVER IN A HYPERCHOLESTEROLEMIC POPULATION OF NORTHWESTERN PENINSULAR MALAYSIA
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