SQUAMOUS CELL CARCINOMA OF THE ORAL CAVITY AND OROPHARYNX IN YOUNG ADULTS

Studies of squamous cell carcinoma of the oral cavity and oropharynx in young adults differ as to whether younger patients resemble the general population of head and neck cancer patients. A retrospective study was performed on 23 patients (40 years old or younger) with oral and oropharyngeal carcin...

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Veröffentlicht in:Head & neck surgery (New York, N.Y.) N.Y.), 1988-03, Vol.10 (4), p.229-234
Hauptverfasser: Cusumano, Robert J., Persky, Mark S.
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container_title Head & neck surgery (New York, N.Y.)
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creator Cusumano, Robert J.
Persky, Mark S.
description Studies of squamous cell carcinoma of the oral cavity and oropharynx in young adults differ as to whether younger patients resemble the general population of head and neck cancer patients. A retrospective study was performed on 23 patients (40 years old or younger) with oral and oropharyngeal carcinoma at New York University Medical Center between 1961 and 1984. Patients with oropharyngeal cancer resembled the general population of head and neck cancer patients. In contrast, oral cavity carcinoma occurred more frequently in women under the age of 35 and lacked the usual etiologic factors of tobacco and alcohol abuse. Survival correlated best with the TNM stage of disease at initial presentation. Patients with Stage I and II lesions had an excellent response to surgical treatment alone and a high 5‐year survival rate. Patients with advanced Stage III and IV disease had a poor survival rate with single modality treatment. We recommend surgery and radiotherapy in patients with advanced disease.
doi_str_mv 10.1002/j.1930-2398.1988.tb00004.x
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A retrospective study was performed on 23 patients (40 years old or younger) with oral and oropharyngeal carcinoma at New York University Medical Center between 1961 and 1984. Patients with oropharyngeal cancer resembled the general population of head and neck cancer patients. In contrast, oral cavity carcinoma occurred more frequently in women under the age of 35 and lacked the usual etiologic factors of tobacco and alcohol abuse. Survival correlated best with the TNM stage of disease at initial presentation. Patients with Stage I and II lesions had an excellent response to surgical treatment alone and a high 5‐year survival rate. Patients with advanced Stage III and IV disease had a poor survival rate with single modality treatment. We recommend surgery and radiotherapy in patients with advanced disease.</abstract><cop>New York, NY</cop><pub>Wiley</pub><pmid>3235353</pmid><doi>10.1002/j.1930-2398.1988.tb00004.x</doi><tpages>6</tpages></addata></record>
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subjects Adult
Age Factors
Biological and medical sciences
Carcinoma, Squamous Cell - epidemiology
Carcinoma, Squamous Cell - mortality
Carcinoma, Squamous Cell - therapy
Female
Humans
Male
Medical sciences
Mouth Neoplasms - epidemiology
Mouth Neoplasms - mortality
Mouth Neoplasms - therapy
Neoplasm Recurrence, Local
Oropharyngeal Neoplasms - epidemiology
Oropharyngeal Neoplasms - mortality
Oropharyngeal Neoplasms - therapy
Otorhinolaryngology. Stomatology
Pharyngeal Neoplasms - epidemiology
Retrospective Studies
Sex Factors
Tumors
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
title SQUAMOUS CELL CARCINOMA OF THE ORAL CAVITY AND OROPHARYNX IN YOUNG ADULTS
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