Results of Endocavitary Irradiation of Early Rectal Tumors
At the C. G. F. Leclerc, Dijon, 91 early rectal tumors were treated with intracavitary contact radiotherapy alone or in combination with interstitial brachytherapy. The median age of the patients was 70 years. Most of them were referred because of poor surgical risk. Preservation of the sphincter wa...
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| Veröffentlicht in: | Acta oncologica 1988, Vol.27 (6), p.825-827 |
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| creator | Roth, S. L. Horiot, J. C. Calais, G. Nabid, A. Bone, M. C. |
| description | At the C. G. F. Leclerc, Dijon, 91 early rectal tumors were treated with intracavitary contact radiotherapy alone or in combination with interstitial brachytherapy. The median age of the patients was 70 years. Most of them were referred because of poor surgical risk. Preservation of the sphincter was obtained in 85% (77/91). The actuarial local relapse-free survival rate at 5 years was 74% (67/91). No significant difference was seen between the 72 adenocarcinomas and 19 villous adenomas (p=0.12). For the middle rectum the rate was 94% compared to 54% for the upper and 77% for the lower rectum. Anterior primaries fared better than posterior and lateral tumors (100%, 63%, and 67% respectively). After salvage therapy the local control rate raised to 91% (83/91). The clinical and endoscopic staging system of Dijon was of prognostic significance: T1A adenocarcinomas (purely exophytic tumors of less than 3 cm) had a better 5-year local relapse-free survival rate (97%) than T2A, T1B or T2B (p < 5.01). |
| doi_str_mv | 10.3109/02841868809094367 |
| format | Article |
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L. ; Horiot, J. C. ; Calais, G. ; Nabid, A. ; Bone, M. C.</creator><creatorcontrib>Roth, S. L. ; Horiot, J. C. ; Calais, G. ; Nabid, A. ; Bone, M. C.</creatorcontrib><description>At the C. G. F. Leclerc, Dijon, 91 early rectal tumors were treated with intracavitary contact radiotherapy alone or in combination with interstitial brachytherapy. The median age of the patients was 70 years. Most of them were referred because of poor surgical risk. Preservation of the sphincter was obtained in 85% (77/91). The actuarial local relapse-free survival rate at 5 years was 74% (67/91). No significant difference was seen between the 72 adenocarcinomas and 19 villous adenomas (p=0.12). For the middle rectum the rate was 94% compared to 54% for the upper and 77% for the lower rectum. Anterior primaries fared better than posterior and lateral tumors (100%, 63%, and 67% respectively). After salvage therapy the local control rate raised to 91% (83/91). The clinical and endoscopic staging system of Dijon was of prognostic significance: T1A adenocarcinomas (purely exophytic tumors of less than 3 cm) had a better 5-year local relapse-free survival rate (97%) than T2A, T1B or T2B (p < 5.01).</description><identifier>ISSN: 0284-186X</identifier><identifier>EISSN: 1651-226X</identifier><identifier>DOI: 10.3109/02841868809094367</identifier><identifier>PMID: 3233169</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Adenocarcinoma - radiotherapy ; Adenoma - radiotherapy ; Adult ; Aged ; Aged, 80 and over ; Brachytherapy ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Prognosis ; Rectal Neoplasms - mortality ; Rectal Neoplasms - pathology ; Rectal Neoplasms - radiotherapy</subject><ispartof>Acta oncologica, 1988, Vol.27 (6), p.825-827</ispartof><rights>1988 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1988</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c391t-7f047d3749b94322f1a9053433d201723f39b437d67fff299a18a36dba20eaab3</citedby><cites>FETCH-LOGICAL-c391t-7f047d3749b94322f1a9053433d201723f39b437d67fff299a18a36dba20eaab3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/02841868809094367$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/02841868809094367$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,780,784,4014,27914,27915,27916,61210,61391</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3233169$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Roth, S. L.</creatorcontrib><creatorcontrib>Horiot, J. C.</creatorcontrib><creatorcontrib>Calais, G.</creatorcontrib><creatorcontrib>Nabid, A.</creatorcontrib><creatorcontrib>Bone, M. C.</creatorcontrib><title>Results of Endocavitary Irradiation of Early Rectal Tumors</title><title>Acta oncologica</title><addtitle>Acta Oncol</addtitle><description>At the C. G. F. Leclerc, Dijon, 91 early rectal tumors were treated with intracavitary contact radiotherapy alone or in combination with interstitial brachytherapy. The median age of the patients was 70 years. Most of them were referred because of poor surgical risk. Preservation of the sphincter was obtained in 85% (77/91). The actuarial local relapse-free survival rate at 5 years was 74% (67/91). No significant difference was seen between the 72 adenocarcinomas and 19 villous adenomas (p=0.12). For the middle rectum the rate was 94% compared to 54% for the upper and 77% for the lower rectum. Anterior primaries fared better than posterior and lateral tumors (100%, 63%, and 67% respectively). After salvage therapy the local control rate raised to 91% (83/91). The clinical and endoscopic staging system of Dijon was of prognostic significance: T1A adenocarcinomas (purely exophytic tumors of less than 3 cm) had a better 5-year local relapse-free survival rate (97%) than T2A, T1B or T2B (p < 5.01).</description><subject>Adenocarcinoma - radiotherapy</subject><subject>Adenoma - radiotherapy</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Brachytherapy</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neoplasm Staging</subject><subject>Prognosis</subject><subject>Rectal Neoplasms - mortality</subject><subject>Rectal Neoplasms - pathology</subject><subject>Rectal Neoplasms - radiotherapy</subject><issn>0284-186X</issn><issn>1651-226X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEFLw0AQhRdRaq3-AA9CTt6isztpNqsnKVULBaFU6C1Mkl2akmTrblLovze1xYvgaQ7fe495j7FbDg_IQT2CSCKexEkCClSEsTxjQx6PeShEvDpnwwMPe8Hqkl15vwEAgXI8YAMUiDxWQ_a00L6rWh9YE0ybwua0K1ty-2DmHBUltaVtfhi5ah8sdN5SFSy72jp_zS4MVV7fnO6Ifb5Ol5P3cP7xNpu8zMMcFW9DaSCSBcpIZf2LQhhOCsYYIRYCuBRoUGURyiKWxhihFPGEMC4yEqCJMhyx-2Pu1tmvTvs2rUuf66qiRtvOpzKRAEnfbMT4UZg7673TJt26su7LpBzSw17pn716z90pvMtqXfw6TgP1_PnIy8ZYV9NaU9Wuc3I63djONX3xf9K_ASIldqY</recordid><startdate>1988</startdate><enddate>1988</enddate><creator>Roth, S. L.</creator><creator>Horiot, J. C.</creator><creator>Calais, G.</creator><creator>Nabid, A.</creator><creator>Bone, M. C.</creator><general>Informa UK Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1988</creationdate><title>Results of Endocavitary Irradiation of Early Rectal Tumors</title><author>Roth, S. L. ; Horiot, J. C. ; Calais, G. ; Nabid, A. ; Bone, M. C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c391t-7f047d3749b94322f1a9053433d201723f39b437d67fff299a18a36dba20eaab3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Adenocarcinoma - radiotherapy</topic><topic>Adenoma - radiotherapy</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Brachytherapy</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neoplasm Staging</topic><topic>Prognosis</topic><topic>Rectal Neoplasms - mortality</topic><topic>Rectal Neoplasms - pathology</topic><topic>Rectal Neoplasms - radiotherapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Roth, S. L.</creatorcontrib><creatorcontrib>Horiot, J. C.</creatorcontrib><creatorcontrib>Calais, G.</creatorcontrib><creatorcontrib>Nabid, A.</creatorcontrib><creatorcontrib>Bone, M. C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta oncologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Roth, S. L.</au><au>Horiot, J. C.</au><au>Calais, G.</au><au>Nabid, A.</au><au>Bone, M. C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Results of Endocavitary Irradiation of Early Rectal Tumors</atitle><jtitle>Acta oncologica</jtitle><addtitle>Acta Oncol</addtitle><date>1988</date><risdate>1988</risdate><volume>27</volume><issue>6</issue><spage>825</spage><epage>827</epage><pages>825-827</pages><issn>0284-186X</issn><eissn>1651-226X</eissn><abstract>At the C. G. F. Leclerc, Dijon, 91 early rectal tumors were treated with intracavitary contact radiotherapy alone or in combination with interstitial brachytherapy. The median age of the patients was 70 years. Most of them were referred because of poor surgical risk. Preservation of the sphincter was obtained in 85% (77/91). The actuarial local relapse-free survival rate at 5 years was 74% (67/91). No significant difference was seen between the 72 adenocarcinomas and 19 villous adenomas (p=0.12). For the middle rectum the rate was 94% compared to 54% for the upper and 77% for the lower rectum. Anterior primaries fared better than posterior and lateral tumors (100%, 63%, and 67% respectively). After salvage therapy the local control rate raised to 91% (83/91). The clinical and endoscopic staging system of Dijon was of prognostic significance: T1A adenocarcinomas (purely exophytic tumors of less than 3 cm) had a better 5-year local relapse-free survival rate (97%) than T2A, T1B or T2B (p < 5.01).</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>3233169</pmid><doi>10.3109/02841868809094367</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0284-186X |
| ispartof | Acta oncologica, 1988, Vol.27 (6), p.825-827 |
| issn | 0284-186X 1651-226X |
| language | eng |
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| source | MEDLINE; Taylor & Francis Journals Complete; EZB Electronic Journals Library |
| subjects | Adenocarcinoma - radiotherapy Adenoma - radiotherapy Adult Aged Aged, 80 and over Brachytherapy Female Humans Male Middle Aged Neoplasm Staging Prognosis Rectal Neoplasms - mortality Rectal Neoplasms - pathology Rectal Neoplasms - radiotherapy |
| title | Results of Endocavitary Irradiation of Early Rectal Tumors |
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