Protective metabolic mechanisms during liver ischemia: transferable lessons from long-diving animals

During periods of O2 lack in liver of seals, mitochondrial respiration and adenosine triphosphate (ATP) synthesis are necessarily arrested. During such electron transfer system (ETS) arrest, the mitochondria are suspended in functionally protected states; upon resupplying O2 and adenosine diphosphat...

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Veröffentlicht in:	Molecular and cellular biochemistry 1988-11, Vol.84 (1), p.77-85
Hauptverfasser:	Hochachka, P W, Castellini, J M, Hill, R D, Schneider, R C, Bengtson, J L, Hill, S E, Liggins, G C, Zapol, W M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caniformia - metabolism Diving - adverse effects Glycolysis Hypoxia - metabolism Ischemia - metabolism Liver - blood supply Mitochondria, Liver - metabolism Oxygen Consumption Potassium - metabolism Seals, Earless - metabolism Space life sciences
Online-Zugang:	Volltext
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