Changes in Radiation Sensitivity and Steroid Receptor Content Induced by Hormonal Agents and Ionizing Radiation in Breast Cancer Cells in Vitro

Possible influences of tamoxifen and estradiol on in vitro radiation sensitivity and cellular receptor content after irradiation and/or tamoxifen treatment were studied in breast cancer cell lines; estrogen receptor (ER) and progesterone receptor (PgR) positive cell lines MCF-7 and MCF-7/TAMR-1 and...

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Veröffentlicht in:	Acta oncologica 1996, Vol.35 (8), p.1011-1019
Hauptverfasser:	Paulsen, Gudrun H. U., Strickert, Trond, Marthinsen, Anne B. L., Lundgren, Steinar
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Antineoplastic Agents, Hormonal - pharmacology Antineoplastic Agents, Hormonal - therapeutic use Biological and medical sciences Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Breast Neoplasms - physiopathology Breast Neoplasms - radiotherapy Cell Survival - radiation effects Chemotherapy, Adjuvant Combined treatments (chemotherapy of immunotherapy associated with an other treatment) Cytosol - metabolism Estradiol - pharmacology Estradiol - therapeutic use Female Gene Expression Regulation, Neoplastic Humans Medical sciences Pharmacology. Drug treatments Radiation Tolerance - drug effects Radiotherapy Dosage Radiotherapy, Adjuvant Receptors, Estrogen - metabolism Receptors, Progesterone - metabolism Tamoxifen - pharmacology Tamoxifen - therapeutic use Tumor Cells, Cultured
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