Urine-based diagnostic technologies
The worldwide dissemination of infectious agents has created a demand for simple diagnostic tests. Urine-based testing makes use of non-invasive collection of specimens, and there is no need for expensive facilities and equipment, or for highly trained personnel. As urine antibodies retain activity...
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| Veröffentlicht in: | Trends in biotechnology (Regular ed.) 1996-10, Vol.14 (10), p.361-364 |
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| container_end_page | 364 |
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| container_issue | 10 |
| container_start_page | 361 |
| container_title | Trends in biotechnology (Regular ed.) |
| container_volume | 14 |
| creator | Urnovitz, Howard B. Murphy, William H. Gottfried, Toby D. Friedman-Kien, Alvin E. |
| description | The worldwide dissemination of infectious agents has created a demand for simple diagnostic tests. Urine-based testing makes use of non-invasive collection of specimens, and there is no need for expensive facilities and equipment, or for highly trained personnel. As urine antibodies retain activity under normal conditions of transport and storage, such tests appear to have widespread application. Urine-based antibody tests have also indicated a compartmentalized antibody response to HIV-1 infection. Urine studies suggest that antibodies to the products of endogenous viral genes may be involved in the pathogenesis of chronic diseases of suspected viral etiology. |
| doi_str_mv | 10.1016/0167-7799(96)10048-2 |
| format | Article |
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Urine-based testing makes use of non-invasive collection of specimens, and there is no need for expensive facilities and equipment, or for highly trained personnel. As urine antibodies retain activity under normal conditions of transport and storage, such tests appear to have widespread application. Urine-based antibody tests have also indicated a compartmentalized antibody response to HIV-1 infection. 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Urine-based testing makes use of non-invasive collection of specimens, and there is no need for expensive facilities and equipment, or for highly trained personnel. As urine antibodies retain activity under normal conditions of transport and storage, such tests appear to have widespread application. Urine-based antibody tests have also indicated a compartmentalized antibody response to HIV-1 infection. Urine studies suggest that antibodies to the products of endogenous viral genes may be involved in the pathogenesis of chronic diseases of suspected viral etiology.</description><subject>AIDS/HIV</subject><subject>Antibodies - urine</subject><subject>Bacterial arthritis and osteitis</subject><subject>Bacterial diseases</subject><subject>Biological and medical sciences</subject><subject>Biomarkers - urine</subject><subject>Biotechnology</subject><subject>Communicable Diseases - diagnosis</subject><subject>Communicable Diseases - urine</subject><subject>HIV Antibodies - urine</subject><subject>HIV Infections - diagnosis</subject><subject>HIV Infections - immunology</subject><subject>HIV-1 - immunology</subject><subject>Human bacterial diseases</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunodeficiencies</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunopathology</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Viral diseases</subject><issn>0167-7799</issn><issn>1879-3096</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1Lw0AQhhdRaq3-A4WCInqI7vdkL4IUv6DgxZ6XzWZSV9Kk7qaC_97Ulh71MMxhnnmZeQg5ZfSGUaZv-4IMwJgro68ZpTLP-B4ZshxMJqjR-2S4Qw7JUUoflFIBhg3IIDc5aCGG5HwWQ4NZ4RKW4zK4edOmLvhxh_69aet2HjAdk4PK1QlPtn1EZo8Pb5PnbPr69DK5n2ZeMugyMAi5koKX1FToKSuUKT0UlcQCQJYFglZKARWOc4WKc-O0UJWDwikujRiRy03uMrafK0ydXYTksa5dg-0qWci1yoXg_4JMmf7TXPag3IA-tilFrOwyhoWL35ZRu5Zo14bs2pA12v5KtOv8s23-qlhguVvaWuvnF9u5S97VVXSND2mHcQlSA_TY3QbDXtpXwGiTD9h4LENE39myDX_f8QMj8Ytq</recordid><startdate>19961001</startdate><enddate>19961001</enddate><creator>Urnovitz, Howard B.</creator><creator>Murphy, William H.</creator><creator>Gottfried, Toby D.</creator><creator>Friedman-Kien, Alvin E.</creator><general>Elsevier Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>19961001</creationdate><title>Urine-based diagnostic technologies</title><author>Urnovitz, Howard B. ; Murphy, William H. ; Gottfried, Toby D. ; Friedman-Kien, Alvin E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-79e785432d09fec01b59dc7bf4eb774dbe76555703a225e5229a635fa7ba52493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>AIDS/HIV</topic><topic>Antibodies - urine</topic><topic>Bacterial arthritis and osteitis</topic><topic>Bacterial diseases</topic><topic>Biological and medical sciences</topic><topic>Biomarkers - urine</topic><topic>Biotechnology</topic><topic>Communicable Diseases - diagnosis</topic><topic>Communicable Diseases - urine</topic><topic>HIV Antibodies - urine</topic><topic>HIV Infections - diagnosis</topic><topic>HIV Infections - immunology</topic><topic>HIV-1 - immunology</topic><topic>Human bacterial diseases</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Immunodeficiencies</topic><topic>Immunodeficiencies. 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| fulltext | fulltext |
| identifier | ISSN: 0167-7799 |
| ispartof | Trends in biotechnology (Regular ed.), 1996-10, Vol.14 (10), p.361-364 |
| issn | 0167-7799 1879-3096 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78658332 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | AIDS/HIV Antibodies - urine Bacterial arthritis and osteitis Bacterial diseases Biological and medical sciences Biomarkers - urine Biotechnology Communicable Diseases - diagnosis Communicable Diseases - urine HIV Antibodies - urine HIV Infections - diagnosis HIV Infections - immunology HIV-1 - immunology Human bacterial diseases Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Medical sciences Miscellaneous Viral diseases |
| title | Urine-based diagnostic technologies |
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