Genetic mapping of 18S ribosomal RNA-related loci to mouse chromosomes 5, 6, 9, 12, 17, 18, 19, and X
The organization of ribosomal RNA genes (rDNA) in the genome of the mouse varies significantly from one strain to another, but has been shown to follow the pattern of clusters of tandem repeats located at chromosome ends, often associated with cytological nucleolus organizer regions. The number of c...
Gespeichert in:
| Veröffentlicht in: | Mammalian genome 1996-12, Vol.7 (12), p.886-889 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 889 |
|---|---|
| container_issue | 12 |
| container_start_page | 886 |
| container_title | Mammalian genome |
| container_volume | 7 |
| creator | Rowe, L B Janaswami, P M Barter, M E Birkenmeier, E H |
| description | The organization of ribosomal RNA genes (rDNA) in the genome of the mouse varies significantly from one strain to another, but has been shown to follow the pattern of clusters of tandem repeats located at chromosome ends, often associated with cytological nucleolus organizer regions. The number of copies of the repeat unit at each locus also varies. A probe for the 18S ribosomal RNA sequence on Southern blots reveals both high copy number bands and fainter bands indicative of low repeat number. We have mapped a number of newly identified low-copy-number rDNA loci in C57BL/6J, in addition to placing some of the NOR-associated rDNA repeats on the Jackson interspecific backcross (BSS) map. We suggest that additional low-copy-number loci may remain to be mapped, and that the evolution of rDNA loci in the genome may include the proliferation of single copies by retroinsertion or other mechanisms. |
| doi_str_mv | 10.1007/s003359900262 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78657402</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>78657402</sourcerecordid><originalsourceid>FETCH-LOGICAL-c385t-d006e593a2a9e365ffbb5622f4adb06b68b955d7af1059f37f27097a2c44de583</originalsourceid><addsrcrecordid>eNqFkM1LxDAQxYMo67p69Cjk5Gmrk6T5Oi6LrsKi4Ad4K2mbaKVtatI9-N-bZRfBk4fHMDM_Ho-H0DmBKwIgryMAY1xrACroAZqSnNGMSCkP0RQ0U5lKv2N0EuMnAJGCyAmapBuXXE2RXdnejk2FOzMMTf-OvcNEPePQlD76zrT46WGRBdua0da49VWDR487v4kWVx_Bd1vKRsznWMyxnmNCk2SSSkq76Wv8doqOnGmjPdvPGXq9vXlZ3mXrx9X9crHOKqb4mNUAwnLNDDXaMsGdK0suKHW5qUsQpVCl5ryWxhHg2jHpqAQtDa3yvLZcsRm63PkOwX9tbByLromVbVvT2xS5kEpwmQP9FyQphVJCJDDbgVXwMQbriiE0nQnfBYFi23_xp__EX-yNN2Vn6196Xzj7AcSCeqY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>15938866</pqid></control><display><type>article</type><title>Genetic mapping of 18S ribosomal RNA-related loci to mouse chromosomes 5, 6, 9, 12, 17, 18, 19, and X</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Rowe, L B ; Janaswami, P M ; Barter, M E ; Birkenmeier, E H</creator><creatorcontrib>Rowe, L B ; Janaswami, P M ; Barter, M E ; Birkenmeier, E H</creatorcontrib><description>The organization of ribosomal RNA genes (rDNA) in the genome of the mouse varies significantly from one strain to another, but has been shown to follow the pattern of clusters of tandem repeats located at chromosome ends, often associated with cytological nucleolus organizer regions. The number of copies of the repeat unit at each locus also varies. A probe for the 18S ribosomal RNA sequence on Southern blots reveals both high copy number bands and fainter bands indicative of low repeat number. We have mapped a number of newly identified low-copy-number rDNA loci in C57BL/6J, in addition to placing some of the NOR-associated rDNA repeats on the Jackson interspecific backcross (BSS) map. We suggest that additional low-copy-number loci may remain to be mapped, and that the evolution of rDNA loci in the genome may include the proliferation of single copies by retroinsertion or other mechanisms.</description><identifier>ISSN: 0938-8990</identifier><identifier>EISSN: 1432-1777</identifier><identifier>DOI: 10.1007/s003359900262</identifier><identifier>PMID: 8995758</identifier><language>eng</language><publisher>United States</publisher><subject>Animals ; Chromosome Mapping ; DNA, Ribosomal ; Female ; Male ; Mice ; Mice, Inbred C57BL ; RNA, Ribosomal, 18S ; X Chromosome</subject><ispartof>Mammalian genome, 1996-12, Vol.7 (12), p.886-889</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c385t-d006e593a2a9e365ffbb5622f4adb06b68b955d7af1059f37f27097a2c44de583</citedby><cites>FETCH-LOGICAL-c385t-d006e593a2a9e365ffbb5622f4adb06b68b955d7af1059f37f27097a2c44de583</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8995758$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rowe, L B</creatorcontrib><creatorcontrib>Janaswami, P M</creatorcontrib><creatorcontrib>Barter, M E</creatorcontrib><creatorcontrib>Birkenmeier, E H</creatorcontrib><title>Genetic mapping of 18S ribosomal RNA-related loci to mouse chromosomes 5, 6, 9, 12, 17, 18, 19, and X</title><title>Mammalian genome</title><addtitle>Mamm Genome</addtitle><description>The organization of ribosomal RNA genes (rDNA) in the genome of the mouse varies significantly from one strain to another, but has been shown to follow the pattern of clusters of tandem repeats located at chromosome ends, often associated with cytological nucleolus organizer regions. The number of copies of the repeat unit at each locus also varies. A probe for the 18S ribosomal RNA sequence on Southern blots reveals both high copy number bands and fainter bands indicative of low repeat number. We have mapped a number of newly identified low-copy-number rDNA loci in C57BL/6J, in addition to placing some of the NOR-associated rDNA repeats on the Jackson interspecific backcross (BSS) map. We suggest that additional low-copy-number loci may remain to be mapped, and that the evolution of rDNA loci in the genome may include the proliferation of single copies by retroinsertion or other mechanisms.</description><subject>Animals</subject><subject>Chromosome Mapping</subject><subject>DNA, Ribosomal</subject><subject>Female</subject><subject>Male</subject><subject>Mice</subject><subject>Mice, Inbred C57BL</subject><subject>RNA, Ribosomal, 18S</subject><subject>X Chromosome</subject><issn>0938-8990</issn><issn>1432-1777</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1LxDAQxYMo67p69Cjk5Gmrk6T5Oi6LrsKi4Ad4K2mbaKVtatI9-N-bZRfBk4fHMDM_Ho-H0DmBKwIgryMAY1xrACroAZqSnNGMSCkP0RQ0U5lKv2N0EuMnAJGCyAmapBuXXE2RXdnejk2FOzMMTf-OvcNEPePQlD76zrT46WGRBdua0da49VWDR487v4kWVx_Bd1vKRsznWMyxnmNCk2SSSkq76Wv8doqOnGmjPdvPGXq9vXlZ3mXrx9X9crHOKqb4mNUAwnLNDDXaMsGdK0suKHW5qUsQpVCl5ryWxhHg2jHpqAQtDa3yvLZcsRm63PkOwX9tbByLromVbVvT2xS5kEpwmQP9FyQphVJCJDDbgVXwMQbriiE0nQnfBYFi23_xp__EX-yNN2Vn6196Xzj7AcSCeqY</recordid><startdate>19961201</startdate><enddate>19961201</enddate><creator>Rowe, L B</creator><creator>Janaswami, P M</creator><creator>Barter, M E</creator><creator>Birkenmeier, E H</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>19961201</creationdate><title>Genetic mapping of 18S ribosomal RNA-related loci to mouse chromosomes 5, 6, 9, 12, 17, 18, 19, and X</title><author>Rowe, L B ; Janaswami, P M ; Barter, M E ; Birkenmeier, E H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c385t-d006e593a2a9e365ffbb5622f4adb06b68b955d7af1059f37f27097a2c44de583</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Animals</topic><topic>Chromosome Mapping</topic><topic>DNA, Ribosomal</topic><topic>Female</topic><topic>Male</topic><topic>Mice</topic><topic>Mice, Inbred C57BL</topic><topic>RNA, Ribosomal, 18S</topic><topic>X Chromosome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rowe, L B</creatorcontrib><creatorcontrib>Janaswami, P M</creatorcontrib><creatorcontrib>Barter, M E</creatorcontrib><creatorcontrib>Birkenmeier, E H</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Mammalian genome</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rowe, L B</au><au>Janaswami, P M</au><au>Barter, M E</au><au>Birkenmeier, E H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genetic mapping of 18S ribosomal RNA-related loci to mouse chromosomes 5, 6, 9, 12, 17, 18, 19, and X</atitle><jtitle>Mammalian genome</jtitle><addtitle>Mamm Genome</addtitle><date>1996-12-01</date><risdate>1996</risdate><volume>7</volume><issue>12</issue><spage>886</spage><epage>889</epage><pages>886-889</pages><issn>0938-8990</issn><eissn>1432-1777</eissn><abstract>The organization of ribosomal RNA genes (rDNA) in the genome of the mouse varies significantly from one strain to another, but has been shown to follow the pattern of clusters of tandem repeats located at chromosome ends, often associated with cytological nucleolus organizer regions. The number of copies of the repeat unit at each locus also varies. A probe for the 18S ribosomal RNA sequence on Southern blots reveals both high copy number bands and fainter bands indicative of low repeat number. We have mapped a number of newly identified low-copy-number rDNA loci in C57BL/6J, in addition to placing some of the NOR-associated rDNA repeats on the Jackson interspecific backcross (BSS) map. We suggest that additional low-copy-number loci may remain to be mapped, and that the evolution of rDNA loci in the genome may include the proliferation of single copies by retroinsertion or other mechanisms.</abstract><cop>United States</cop><pmid>8995758</pmid><doi>10.1007/s003359900262</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0938-8990 |
| ispartof | Mammalian genome, 1996-12, Vol.7 (12), p.886-889 |
| issn | 0938-8990 1432-1777 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78657402 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Animals Chromosome Mapping DNA, Ribosomal Female Male Mice Mice, Inbred C57BL RNA, Ribosomal, 18S X Chromosome |
| title | Genetic mapping of 18S ribosomal RNA-related loci to mouse chromosomes 5, 6, 9, 12, 17, 18, 19, and X |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T12%3A25%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Genetic%20mapping%20of%2018S%20ribosomal%20RNA-related%20loci%20to%20mouse%20chromosomes%205,%206,%209,%2012,%2017,%2018,%2019,%20and%20X&rft.jtitle=Mammalian%20genome&rft.au=Rowe,%20L%20B&rft.date=1996-12-01&rft.volume=7&rft.issue=12&rft.spage=886&rft.epage=889&rft.pages=886-889&rft.issn=0938-8990&rft.eissn=1432-1777&rft_id=info:doi/10.1007/s003359900262&rft_dat=%3Cproquest_cross%3E78657402%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=15938866&rft_id=info:pmid/8995758&rfr_iscdi=true |