Origin of high acetylcholinesterase activity in the mouse superior colliculus
The acetylcholinesterase activity in the colliculus mainly occurs in two layers and is arranged as a lattice in the intermediate grey layer and as a continuous sheet in the superficial grey layer. Undercutting lesions abolish the lattice in the intermediate grey layer but leave the superficial sheet...
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| Veröffentlicht in: | Experimental brain research 1988-01, Vol.72 (2), p.335-346 |
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| creator | WALLACE, M. N FREDENS, K |
| description | The acetylcholinesterase activity in the colliculus mainly occurs in two layers and is arranged as a lattice in the intermediate grey layer and as a continuous sheet in the superficial grey layer. Undercutting lesions abolish the lattice in the intermediate grey layer but leave the superficial sheet of activity intact. By contrast the injection of kainic acid into the colliculus leaves the intermediate layer lattice intact while causing a local reduction in the superficial layer. Injections of the retrograde tracer Fluoro-Gold into the colliculus labels cells in the pedunculopontine and laterodorsal tegmental nuclei that contains acetylcholinesterase. Cells in the parabigeminal nucleus are also labelled but these cells contain low levels of cholinesterase. Thus, it is concluded that the lattice in the intermediate layers is mainly dependent on afferents from the laterodorsal tegmental and pedunculopontine nuclei while the sheet in the superficial layers is mainly dependent on intrinsic cells. |
| doi_str_mv | 10.1007/bf00250255 |
| format | Article |
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Thus, it is concluded that the lattice in the intermediate layers is mainly dependent on afferents from the laterodorsal tegmental and pedunculopontine nuclei while the sheet in the superficial layers is mainly dependent on intrinsic cells.</description><identifier>ISSN: 0014-4819</identifier><identifier>EISSN: 1432-1106</identifier><identifier>DOI: 10.1007/bf00250255</identifier><identifier>PMID: 2465171</identifier><identifier>CODEN: EXBRAP</identifier><language>eng</language><publisher>Berlin: Springer</publisher><subject>Acetylcholinesterase - metabolism ; Animals ; Axonal Transport ; Biological and medical sciences ; Brain - anatomy & histology ; Brain Stem - physiology ; Central nervous system ; Central neurotransmission. Neuromudulation. Pathways and receptors ; Fundamental and applied biological sciences. 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Cells in the parabigeminal nucleus are also labelled but these cells contain low levels of cholinesterase. Thus, it is concluded that the lattice in the intermediate layers is mainly dependent on afferents from the laterodorsal tegmental and pedunculopontine nuclei while the sheet in the superficial layers is mainly dependent on intrinsic cells.</description><subject>Acetylcholinesterase - metabolism</subject><subject>Animals</subject><subject>Axonal Transport</subject><subject>Biological and medical sciences</subject><subject>Brain - anatomy & histology</subject><subject>Brain Stem - physiology</subject><subject>Central nervous system</subject><subject>Central neurotransmission. Neuromudulation. Pathways and receptors</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Histocytochemistry</subject><subject>Mice</subject><subject>Reference Values</subject><subject>Staining and Labeling</subject><subject>Superior Colliculi - enzymology</subject><subject>Superior Colliculi - physiology</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0014-4819</issn><issn>1432-1106</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1Lw0AQxRdRaq1evAs5iAchOvuVTY5arAqVXvQcNpNNu7Jp6m4i9L93S6tXYWCY9348hkfIJYU7CqDuqwaAyTjyiIyp4CylFLJjMgagIhU5LU7JWQifu5MrGJERE5mkio7J28LbpV0nXZOs7HKVaDT91uGqc3ZtQm-8DiaKvf22_TaJYL8ySdsNUQ3Dxnjb-QQ75ywObgjn5KTRLpiLw56Qj9nT-_QlnS-eX6cP8xQF5H1KOedYAwpT1zkqrIxkCIIa5KjyWtQqR2wqxnKNkkvKGC-A58BNk5miqviE3OxzN777GuKfZWsDGuf02sTfSpVnMov8vyCVIJmQIoK3exB9F4I3TbnxttV-W1IodyWXj7PfkiN8dUgdqtbUf-ih1ehfH3wdULvG6zXa8IcpUAUUlP8AAuKEAA</recordid><startdate>19880101</startdate><enddate>19880101</enddate><creator>WALLACE, M. 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Psychology</topic><topic>Histocytochemistry</topic><topic>Mice</topic><topic>Reference Values</topic><topic>Staining and Labeling</topic><topic>Superior Colliculi - enzymology</topic><topic>Superior Colliculi - physiology</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>WALLACE, M. N</creatorcontrib><creatorcontrib>FREDENS, K</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>WALLACE, M. 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Injections of the retrograde tracer Fluoro-Gold into the colliculus labels cells in the pedunculopontine and laterodorsal tegmental nuclei that contains acetylcholinesterase. Cells in the parabigeminal nucleus are also labelled but these cells contain low levels of cholinesterase. Thus, it is concluded that the lattice in the intermediate layers is mainly dependent on afferents from the laterodorsal tegmental and pedunculopontine nuclei while the sheet in the superficial layers is mainly dependent on intrinsic cells.</abstract><cop>Berlin</cop><pub>Springer</pub><pmid>2465171</pmid><doi>10.1007/bf00250255</doi><tpages>12</tpages></addata></record> |
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| ispartof | Experimental brain research, 1988-01, Vol.72 (2), p.335-346 |
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| language | eng |
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| source | MEDLINE; Springer Online Journals Complete |
| subjects | Acetylcholinesterase - metabolism Animals Axonal Transport Biological and medical sciences Brain - anatomy & histology Brain Stem - physiology Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Fundamental and applied biological sciences. Psychology Histocytochemistry Mice Reference Values Staining and Labeling Superior Colliculi - enzymology Superior Colliculi - physiology Vertebrates: nervous system and sense organs |
| title | Origin of high acetylcholinesterase activity in the mouse superior colliculus |
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