Absorbable Adams-DeWeese Caval Clip: An Experimental Study

Adams-DeWeese caval clips have been shown to be effective in preventing pulmonary embolism. However, the use of Teflon clips constitutes a permanent solution for this transient risk. We tested an absorbable caval clip made of currently available synthetic biodegradable polymers in five female Beagle...

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Veröffentlicht in:Annals of vascular surgery 1996-11, Vol.10 (6), p.517-523
Hauptverfasser: Bonnichon, P., Sarfati, P.O., Santoni, P., Jeanty, I., Meatchi, T., Crougneau, S., Pariente, D., Ming, L. Su
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container_end_page 523
container_issue 6
container_start_page 517
container_title Annals of vascular surgery
container_volume 10
creator Bonnichon, P.
Sarfati, P.O.
Santoni, P.
Jeanty, I.
Meatchi, T.
Crougneau, S.
Pariente, D.
Ming, L. Su
description Adams-DeWeese caval clips have been shown to be effective in preventing pulmonary embolism. However, the use of Teflon clips constitutes a permanent solution for this transient risk. We tested an absorbable caval clip made of currently available synthetic biodegradable polymers in five female Beagle dogs. The polymer used was PLA 96 containing 96% L lactic acid and 4% D lactic acid. After placement through a laparotomy, clips were routinely inspected and samples of the material were collected at regular intervals between 3 and 19 months postoperatively. The characteristics of absorption of PLA 96 in the retroperitoneal space were the same as those previously described in the literature. The clip retained its shape, rigidity, and effectiveness for 7 months. Complete degradation of the clip took between 18 and 19 months. Absorption did not cause a major inflammatory reaction and had no thrombogenic effect. Given the small number of animals studied, these results must be considered preliminary.
doi_str_mv 10.1007/BF02000439
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source MEDLINE; Elsevier ScienceDirect Journals; SpringerLink Journals - AutoHoldings
subjects Animals
Dogs
Equipment Design
Evaluation Studies as Topic
Female
Lactic Acid
Materials Testing
Polymers
Retroperitoneal Space
Vena Cava Filters
title Absorbable Adams-DeWeese Caval Clip: An Experimental Study
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