No loss in total neuron number in the thalamic reticular nucleus and neocortex in the genetic absence epilepsy rats from Strasbourg
The thalamic reticular nucleus (nRt) as well as the neocortex are involved in the bilateral spike- and wave-discharge loop in genetic absence epilepsy rats from Strasbourg (GAERS). Neuron loss in different brain areas has been described in relation to epilepsy with convulsive seizures. We have previ...
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| Veröffentlicht in: | Epilepsy research 1996-12, Vol.26 (1), p.45-48 |
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| container_title | Epilepsy research |
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| creator | Sabers, Anne Møller, Arne Scheel-Krüger, Jørgen Mouritzen Dam, Agnete |
| description | The thalamic reticular nucleus (nRt) as well as the neocortex are involved in the bilateral spike- and wave-discharge loop in genetic absence epilepsy rats from Strasbourg (GAERS). Neuron loss in different brain areas has been described in relation to epilepsy with convulsive seizures. We have previously investigated the ventrolateral/posterior nucleus of thalamus in GAERS and found no neuron loss. We applied the same efficient and unbiased stereological methods to nRt and to neocortex and again found no loss of neurons. The oscillatory properties of nRt are not related to neuron loss. |
| doi_str_mv | 10.1016/S0920-1211(96)00038-1 |
| format | Article |
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The oscillatory properties of nRt are not related to neuron loss.</description><subject>Absence</subject><subject>Animals</subject><subject>Cell Count</subject><subject>Cerebral Cortex - pathology</subject><subject>Cerebral Cortex - physiopathology</subject><subject>Disease Models, Animal</subject><subject>Electrophysiology</subject><subject>Epilepsy</subject><subject>Epilepsy, Absence - genetics</subject><subject>Epilepsy, Absence - pathology</subject><subject>Epilepsy, Absence - physiopathology</subject><subject>Neocortex</subject><subject>Neuron number</subject><subject>Neurons</subject><subject>Rats</subject><subject>Stereology</subject><subject>Thalamic Nuclei - pathology</subject><subject>Thalamic Nuclei - physiopathology</subject><subject>Thalamic reticular nucleus</subject><issn>0920-1211</issn><issn>1872-6844</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1PHSEUhklTc3ur_QkmrJq6mAozwDCrprnRamLq4uqaAHNGMcxwC4ypa_-43I-67YKQcJ6Xc86D0Ckl3ymh4nxNuppUtKb0WyfOCCGNrOgHtKSyrSshGfuIlu_IJ_Q5pacCtYSxBVrITnIh-RK9_g7Yh5Swm3AOWXs8wRzDhKd5NBB3z49QjvZ6dBZHyM7OXscCWA9zwnrqSybYEDP8_cc_wLQFsTYJJgsYNs7DJr3gqHPCQwwjXueokwlzfDhBR4P2Cb4c7mN0f3lxt7qqbm5_Xa9-3lS2ESRXULN6ANPzmkErGzCG9aBl27UcoCfQcmNbyYg2zA68oRwEkKa22nDbiUE3x-jr_t9NDH9mSFmNLlnwXpf556RaKRhjdVNAvgdtLGoiDGoT3ajji6JEbeWrnXy1Nas6oXbyFS2500OD2YzQv6cOtkv9x74OZctnB1El67Z-ehfBZtUH958Ob-3Yl1c</recordid><startdate>19961201</startdate><enddate>19961201</enddate><creator>Sabers, Anne</creator><creator>Møller, Arne</creator><creator>Scheel-Krüger, Jørgen</creator><creator>Mouritzen Dam, Agnete</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19961201</creationdate><title>No loss in total neuron number in the thalamic reticular nucleus and neocortex in the genetic absence epilepsy rats from Strasbourg</title><author>Sabers, Anne ; Møller, Arne ; Scheel-Krüger, Jørgen ; Mouritzen Dam, Agnete</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-e242febd524e783ebb4dea87975eed0e75bc7840ab4cf5315e6e032cab5c96fa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Absence</topic><topic>Animals</topic><topic>Cell Count</topic><topic>Cerebral Cortex - pathology</topic><topic>Cerebral Cortex - physiopathology</topic><topic>Disease Models, Animal</topic><topic>Electrophysiology</topic><topic>Epilepsy</topic><topic>Epilepsy, Absence - genetics</topic><topic>Epilepsy, Absence - pathology</topic><topic>Epilepsy, Absence - physiopathology</topic><topic>Neocortex</topic><topic>Neuron number</topic><topic>Neurons</topic><topic>Rats</topic><topic>Stereology</topic><topic>Thalamic Nuclei - pathology</topic><topic>Thalamic Nuclei - physiopathology</topic><topic>Thalamic reticular nucleus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sabers, Anne</creatorcontrib><creatorcontrib>Møller, Arne</creatorcontrib><creatorcontrib>Scheel-Krüger, Jørgen</creatorcontrib><creatorcontrib>Mouritzen Dam, Agnete</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Epilepsy research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sabers, Anne</au><au>Møller, Arne</au><au>Scheel-Krüger, Jørgen</au><au>Mouritzen Dam, Agnete</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>No loss in total neuron number in the thalamic reticular nucleus and neocortex in the genetic absence epilepsy rats from Strasbourg</atitle><jtitle>Epilepsy research</jtitle><addtitle>Epilepsy Res</addtitle><date>1996-12-01</date><risdate>1996</risdate><volume>26</volume><issue>1</issue><spage>45</spage><epage>48</epage><pages>45-48</pages><issn>0920-1211</issn><eissn>1872-6844</eissn><abstract>The thalamic reticular nucleus (nRt) as well as the neocortex are involved in the bilateral spike- and wave-discharge loop in genetic absence epilepsy rats from Strasbourg (GAERS). 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| fulltext | fulltext |
| identifier | ISSN: 0920-1211 |
| ispartof | Epilepsy research, 1996-12, Vol.26 (1), p.45-48 |
| issn | 0920-1211 1872-6844 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Absence Animals Cell Count Cerebral Cortex - pathology Cerebral Cortex - physiopathology Disease Models, Animal Electrophysiology Epilepsy Epilepsy, Absence - genetics Epilepsy, Absence - pathology Epilepsy, Absence - physiopathology Neocortex Neuron number Neurons Rats Stereology Thalamic Nuclei - pathology Thalamic Nuclei - physiopathology Thalamic reticular nucleus |
| title | No loss in total neuron number in the thalamic reticular nucleus and neocortex in the genetic absence epilepsy rats from Strasbourg |
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