Heparin-Binding Domain of Fibrin Mediates Its Binding to Endothelial Cells

Spreading of human umbilical vein endothelial cells (ECs) on fibrin requires thrombin cleavage of fibrinopeptide B (FPB) and subsequent exposure of the new beta 15-42 N-terminus. To further understand the interactions between ECs and fibrin beta 15-42 sequences, binding of fibrin(ogen) to EC monolay...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 1996-12, Vol.16 (12), p.1544-1551
Hauptverfasser:	Odrljin, Tatjana M, Francis, Charles W, Sporn, Lee Ann, Bunce, Leslie A, Marder, Victor J, Simpson-Haidaris, Patricia J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Atherosclerosis (general aspects, experimental research) Binding Sites - genetics Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cell Adhesion Endothelium, Vascular - cytology Endothelium, Vascular - metabolism Fibrin - genetics Fibrin - metabolism Heparin - metabolism Humans Medical sciences Molecular Sequence Data Protein Binding - genetics
Online-Zugang:	Volltext
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