Effects of locally infused pharmacological agents on spontaneous and sensory-evoked activity of locus coeruleus neurons

Electrophysiological activity of individual locus coeruleus (LC) neurons was recorded in halothane-anesthetized rats before, during, and after the infusion of adrenergic, cholinergic, or peptidergic compounds about 400 μ, m lateral to LC. The alpha-adrenergic agonist clonidine (CLON), in concentrati...

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Veröffentlicht in:	Brain research bulletin 1988-09, Vol.21 (3), p.395-400
Hauptverfasser:	Adams, Lynne M., Foote, Stephen L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine Acetylcholine - pharmacology Action Potentials - drug effects Adrenergic Fibers - drug effects Adrenergic Fibers - physiology Adrenocorticotropic Hormone - pharmacology Adrenocorticotropin hormone Afferent Pathways - physiology Animals Cholinergic Fibers - drug effects Cholinergic Fibers - physiology Clonidine Clonidine - pharmacology Dose-Response Relationship, Drug Drug infusion Electroshock Locus coeruleus Locus Coeruleus - drug effects Locus Coeruleus - physiology Neurons, Afferent - drug effects Neurons, Afferent - physiology Norepinephrine Peptide Fragments - pharmacology Rats
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