Erythrocytes may synthesize their own nitric oxide

The ability of hemoglobin and myoglobin to bind nitric oxide (NO) produced by other cells and circulating vasodilators is well known. To characterize erythrocytes (RBCs), we used NADPH diaphorase labeling, as well as antibodies to the three known types of NO synthase (NOS 1, 2, and 3), and to a mole...

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Veröffentlicht in:	American journal of hypertension 1996-12, Vol.9 (12), p.1214-1219
Hauptverfasser:	Jubelin, Bruno C., Gierman, Joshua L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Biological and medical sciences Blood coagulation. Blood cells calcium binding protein calmodulin Calmodulin - immunology Endothelium, Vascular - innervation Endothelium, Vascular - metabolism erythrocytes Erythrocytes - metabolism Fundamental and applied biological sciences. Psychology General aspects, investigation methods, hemostasis, fibrinolysis Hemoglobins - metabolism human Immunoblotting lymphocytes Male Molecular and cellular biology Muscle, Smooth - innervation Muscle, Smooth - metabolism Myenteric Plexus - metabolism Myoglobin - metabolism NADPH Dehydrogenase - metabolism Neurons - metabolism Neuropeptide Y - immunology Nitric oxide Nitric Oxide - biosynthesis nitric oxide synthase Nitric Oxide Synthase - metabolism rat Rats
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