Microbial killing by human neutrophil cytokineplasts: similar suppressive effects of reversible and irreversible inhibitors of nitric oxide synthase

Employing anucleate, granule‐poor, motile fragments from human blood neutrophils (cytokineplasts; CKP), we previously provided evidence for a new staphylococcal killing pathway for human neutrophils involving reactive nitrogen intermediates: the NO synthase inhibitor Nω‐monomethyl‐L‐argmine (NMMA),...

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Veröffentlicht in:	Journal of leukocyte biology 1996-12, Vol.60 (6), p.753-757
Hauptverfasser:	Malawista, Stephen E., Montgomery, Ruth R., Blaricom, Gretchen
Format:	Artikel
Sprache:	eng
Schlagworte:	Arginine - pharmacology Blood Bactericidal Activity Cytotoxicity, Immunologic Enzyme Inhibitors - pharmacology Humans L‐arginine Neutrophils - immunology Neutrophils - ultrastructure Nitric Oxide Synthase - antagonists & inhibitors Nitric Oxide Synthase - physiology omega-N-Methylarginine - pharmacology Onium Compounds - pharmacology Ornithine - analogs & derivatives Ornithine - pharmacology reactive nitrogen intermediates Serratia marcescens Staphylococcus aureus
Online-Zugang:	Volltext
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