Identification and characterization of imidazoline-binding sites from calf striatum

‘Non-adrenoceptor’-binding sites for [ 3H]clonidine (I 1-sites) and [ 3H]idazoxan (I 2-sites) are identified in calf striatum membranes. The pharmacological profile of both subtypes was investigated by competition binding with the imidazolines idazoxan, cirazoline, Bu 224 (2-(4,5-dihydroimidaz-2-yl)...

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Veröffentlicht in:	European journal of pharmacology 1996-11, Vol.315 (1), p.99-109
Hauptverfasser:	Czerwiec, Eva, De Backer, Jean-Paul, Flamez, Anja, Vauquelin, Georges
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding, Competitive Biological and medical sciences Calf Cattle Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Clonidine - metabolism Conus venom Corpus Striatum - metabolism Fundamental and applied biological sciences. Psychology Guanidines - metabolism Idazoxan - metabolism Imidazoles - metabolism Imidazoline Receptors Imidazoline-binding site Kinetics Monoamine oxidase Receptors, Drug - drug effects Receptors, Drug - metabolism Striatum Vertebrates: nervous system and sense organs
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