8- O-Acetylharpagide is a nonsteroidal ecdysteroid agonist

We have identified a novel nonsteroidal ecdysteroid agonist. This compound was isolated from a methanol extract of Ajuga reptans L. (Lamiaceae) and the structure was identified by spectroscopic methods as 8- O-acetylharpagide. We have characterised this compound as an ecdysteroid agonist in a transa...

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Veröffentlicht in:	Insect biochemistry and molecular biology 1996-06, Vol.26 (6), p.519-523
Hauptverfasser:	Elbrecht, Alex, Chen, Yuli, Jurgens, Tannis, Hensens, Otto D., Zink, Debra L., Beck, Hans T., Balick, Michael J., Borris, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	agonists Ajuga reptans Animals beta-galactosidase binding sites cell differentiation cell lines Drosophila Drosophila - metabolism Drosophila melanogaster Ecdysteroid ecdysteroids ecdysterone Ecdysterone - agonists Ecdysterone - metabolism enzyme activity hormonal regulation hormone receptors Insect Hormones Insecticide iridoid glycosides Molecular Structure Plant Extracts Plants - metabolism Pyrans - chemistry Pyrans - metabolism Receptor Receptors, Steroid - metabolism reporter genes transcriptional activation
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