heartless encodes a fibroblast growth factor receptor (DFR1/DFGF-R2) involved in the directional migration of early mesodermal cells in the Drosophila embryo

After invagination of the mesodermal primordium in the gastrulating Drosophila embryo, the internalized cells migrate in a dorsolateral direction along the overlying ectoderm. This movement generates a stereotyped arrangement of mesodermal cells that is essential for their correct patterning by late...

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Veröffentlicht in:	Genes & development 1996-12, Vol.10 (23), p.3003-3017
Hauptverfasser:	Gisselbrecht, S, Skeath, J B, Doe, C Q, Michelson, A M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Amino Acid Sequence Animals Base Sequence Cell Movement - genetics Drosophila - embryology Drosophila - genetics Drosophila melanogaster Drosophila Proteins Genes, Protozoan - genetics Genes, ras - genetics Genes, ras - physiology Heart - embryology Mesoderm - chemistry Mesoderm - cytology Molecular Sequence Data Muscles - embryology Mutation Phenotype Protein-Tyrosine Kinases Receptors, Fibroblast Growth Factor - genetics Receptors, Fibroblast Growth Factor - physiology
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