Actions of epoxygenase metabolites on the preglomerular vasculature

Epoxygenase metabolites of arachidonic acid are produced by the kidney and have been implicated in the control of renal blood flow. This study examined the preglomerular actions of various epoxyeicosatrienoic acids (EET). By use of the in vitro blood-perfused juxtamedullary nephron preparation, inte...

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Veröffentlicht in:	Journal of the American Society of Nephrology 1996-11, Vol.7 (11), p.2364-2370
Hauptverfasser:	Imig, J D, Navar, L G, Roman, R J, Reddy, K K, Falck, J R
Format:	Artikel
Sprache:	eng
Schlagworte:	8,11,14-Eicosatrienoic Acid - analogs & derivatives 8,11,14-Eicosatrienoic Acid - pharmacology Animals Arterioles - drug effects Arterioles - physiology Endothelium, Vascular - drug effects Endothelium, Vascular - physiology Juxtaglomerular Apparatus - blood supply Juxtaglomerular Apparatus - drug effects Juxtaglomerular Apparatus - metabolism Male Microscopy, Video Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - physiology Oxygenases - pharmacology Prostaglandin-Endoperoxide Synthases - drug effects Prostaglandin-Endoperoxide Synthases - metabolism Rats Rats, Sprague-Dawley Vasoconstriction - drug effects
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