Expression and function of pancreatic beta-cell delayed rectifier K+ channels. Role in stimulus-secretion coupling

Voltage-dependent delayed rectifier K+ channels regulate aspects of both stimulus-secretion and excitation-contraction coupling, but assigning specific roles to these channels has proved problematic. Using transgenically derived insulinoma cells (betaTC3-neo) and beta-cells purified from rodent panc...

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Veröffentlicht in:	The Journal of biological chemistry 1996-12, Vol.271 (50), p.32241-32246
Hauptverfasser:	Roe, M W, Worley, 3rd, J F, Mittal, A A, Kuznetsov, A, DasGupta, S, Mertz, R J, Witherspoon, 3rd, S M, Blair, N, Lancaster, M E, McIntyre, M S, Shehee, W R, Dukes, I D, Philipson, L H
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Aminopyridine - pharmacology Animals Base Sequence Calcium - metabolism Cell Line Delayed Rectifier Potassium Channels Flow Cytometry Glucose - metabolism Islets of Langerhans - chemistry Membrane Potentials Mice Molecular Sequence Data Potassium Channels - chemistry Potassium Channels - genetics Potassium Channels - physiology Potassium Channels, Voltage-Gated Rats Sequence Alignment Shab Potassium Channels Tetraethylammonium Tetraethylammonium Compounds - pharmacology
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