Effects of Proximate Cholesterol Precursors and Steroid Hormones on Mouse Myeloma Growth in Serum-Free Medium

The proximate cholesterol precursors lathosterol, 7-dehydrocholesterol and desmosterol supported the growth of NS-1 and X63 mouse myeloma cells. These cells and X63.653 cells are cholesterol auxotrophs, yet each was able to convert$[^{3}H]lathosterol$to$[^{3}H]cholesterol$. These results are consist...

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Veröffentlicht in:	In Vitro Cellular & Developmental Biology 1988-12, Vol.24 (12), p.1223-1228
Hauptverfasser:	Sato, J. Denry, Hui-Ting Cao, Kayada, Yoshiaki, Cabot, Myles C., Sato, Gordon H., Okamoto, Tetsuji, Clement J. Welsh
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Hydroxysteroid Dehydrogenases - metabolism Animal cells Animals Biological and medical sciences Biotechnology Cell cultures. Hybridization. Fusion Cell Division - drug effects Cell growth Cell lines Cellular metabolism Cholestadienols - pharmacology Cholesterol - metabolism Cholesterol - pharmacology Cholesterols Culture Media Cultured cells Dehydrocholesterols - pharmacology Desmosterol - pharmacology Establishment of new cell lines, improvement of cultural methods, mass cultures Eukaryotic cell cultures Fundamental and applied biological sciences. Psychology Hormones - pharmacology Hydrocortisone - pharmacology Isomerism L cells Methods. Procedures. Technologies Mice Molecular and cellular biology Multiple Myeloma - metabolism Multiple Myeloma - pathology Progesterone - pharmacology Rapid Communications in Cell Biology Steroid hormones Sterols Testosterone - pharmacology Tumor Cells, Cultured
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