Psychobiological modeling of age-related memory changes
Useful models of age-related human and animal memory changes should simulate specific features of cognitive impairment associated with aging. It is necessary but not sufficient to demonstrate that manipulations such as these produced by lesions and drugs cause impairments in some cognitive function...
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| Veröffentlicht in: | Neurobiology of aging 1988-09, Vol.9 (5-6), p.505-506 |
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| container_end_page | 506 |
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| container_issue | 5-6 |
| container_start_page | 505 |
| container_title | Neurobiology of aging |
| container_volume | 9 |
| creator | Lister, Richard G. Sunderland, Trey Weingartner, Herbert J. |
| description | Useful models of age-related human and animal memory changes should simulate specific features of cognitive impairment associated with aging. It is necessary but not sufficient to demonstrate that manipulations such as these produced by lesions and drugs cause impairments in some cognitive function such as memory. A useful model should be able to reproduce a pattern of cognitive changes in which islands of spared versus impaired functioning resemble those associated with aging and differ from those produced by other conditions. This requires the use of research strategies utilizing multivariate treatment and dependent measure designs. The papers in this section illustrate the value of such a research approach. |
| doi_str_mv | 10.1016/S0197-4580(88)80105-2 |
| format | Article |
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It is necessary but not sufficient to demonstrate that manipulations such as these produced by lesions and drugs cause impairments in some cognitive function such as memory. A useful model should be able to reproduce a pattern of cognitive changes in which islands of spared versus impaired functioning resemble those associated with aging and differ from those produced by other conditions. This requires the use of research strategies utilizing multivariate treatment and dependent measure designs. 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| fulltext | fulltext |
| identifier | ISSN: 0197-4580 |
| ispartof | Neurobiology of aging, 1988-09, Vol.9 (5-6), p.505-506 |
| issn | 0197-4580 1558-1497 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78599712 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Aging - physiology Animals Disease Models, Animal Memory Disorders - physiopathology Research Design |
| title | Psychobiological modeling of age-related memory changes |
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