Status of somatostatin receptor messenger RNAs and binding sites in rat brain during kindling epileptogenesis

In situ hybridization histochemistry with somatostatin sst1−sst5 receptor messenger RNA-selective oligoprobes and quantitative receptor autoradiographic binding studies using [125I]Tyr3-octreotide, [Leu8, d-Trp22,125I-Tyr25]somatostatin-28 and [125I]CGP 23996 ([125I]c[Asn-Lys-Asn-Phe-Phe-Trp-Lys-Thr...

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Veröffentlicht in:	Neuroscience 1996-12, Vol.75 (3), p.857-868
Hauptverfasser:	Piwko, C., Thoss, V.S., Samanin, R., Hoyer, D., Vezzani, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	[125I]LTT-SRIF-28 [Leu8, d-Trp22,125I-Tyr25]somatostatin-28 Animals Autoradiography Binding Sites Biological and medical sciences Brain - metabolism c[Asn-Lys-Asn-Phe-Phe-TrpLys-Thr-Tyr-Thr-Ser] CGP 23996 EDTA EEG EGTA electroencephalographic epilepsy ethylenediaminetetraacetate ethyleneglycolbis(aminoethyl ether)tetra-acetate Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Hippocampus - metabolism in situ histochemistry In Situ Hybridization kindled seizure Kindling, Neurologic - metabolism Male Medical sciences Nervous system (semeiology, syndromes) Neurology Rats Rats, Sprague-Dawley Receptors, Somatostatin - metabolism RNA, Messenger - metabolism somatostatin somatostatin (SRIF somatostatin receptor subtype somatotropin release-inhibiting factor SRIF sst sst/SRIF receptors
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