Maternal serum creatine kinase does not predict tubal pregnancy
Our purpose was to validate prospectively the predictive value of maternal serum creatine kinase in the evaluation of ectopic pregnancy. Fifty-one consecutive pregnant first-trimester patients who presented for suspected abnormal pregnancy were enrolled. Maternal serum samples were obtained and assa...
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| Veröffentlicht in: | Journal of assisted reproduction and genetics 1996-10, Vol.13 (9), p.702-704 |
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| container_title | Journal of assisted reproduction and genetics |
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| creator | LINCOLN, S. R DOCKERY, J. R LONG, C. A ROCK, W. A COWAN, B. D |
| description | Our purpose was to validate prospectively the predictive value of maternal serum creatine kinase in the evaluation of ectopic pregnancy.
Fifty-one consecutive pregnant first-trimester patients who presented for suspected abnormal pregnancy were enrolled. Maternal serum samples were obtained and assayed for creatine kinase. Patients were subsequently evaluated for abnormal pregnancy by serial quantitative hCG levels, transvaginal ultrasonography, and surgery when appropriate. A receiver operating characteristic (ROC) curve was generated comparing intrauterine to extrauterine (ectopic) pregnancy.
Of 51 patients, 18 had an ectopic pregnancy, 16 had a spontaneous abortion, and 17 had an ongoing intrauterine pregnancy. The ROC curve revealed that maternal serum creatine kinase had no ability to predict ectopic pregnancy.
Maternal serum creatine kinase is not a reliable predictor of tubal pregnancy. |
| doi_str_mv | 10.1007/BF02066421 |
| format | Article |
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Fifty-one consecutive pregnant first-trimester patients who presented for suspected abnormal pregnancy were enrolled. Maternal serum samples were obtained and assayed for creatine kinase. Patients were subsequently evaluated for abnormal pregnancy by serial quantitative hCG levels, transvaginal ultrasonography, and surgery when appropriate. A receiver operating characteristic (ROC) curve was generated comparing intrauterine to extrauterine (ectopic) pregnancy.
Of 51 patients, 18 had an ectopic pregnancy, 16 had a spontaneous abortion, and 17 had an ongoing intrauterine pregnancy. The ROC curve revealed that maternal serum creatine kinase had no ability to predict ectopic pregnancy.
Maternal serum creatine kinase is not a reliable predictor of tubal pregnancy.</description><identifier>ISSN: 1058-0468</identifier><identifier>EISSN: 1573-7330</identifier><identifier>DOI: 10.1007/BF02066421</identifier><identifier>PMID: 8947816</identifier><identifier>CODEN: JARGE4</identifier><language>eng</language><publisher>New York, NY: Kluwer/Plenum</publisher><subject>Biological and medical sciences ; Biomarkers - blood ; Clinical Enzyme Tests ; Creatine Kinase - blood ; Diseases of mother, fetus and pregnancy ; Female ; Gynecology. Andrology. Obstetrics ; Humans ; Medical sciences ; Predictive Value of Tests ; Pregnancy ; Pregnancy Trimester, First ; Pregnancy, Ectopic - diagnosis ; Pregnancy. Fetus. Placenta ; Prospective Studies ; Reproducibility of Results ; ROC Curve</subject><ispartof>Journal of assisted reproduction and genetics, 1996-10, Vol.13 (9), p.702-704</ispartof><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c311t-1db4d9dbdc53a7198a0749764c31665cd8162f5fb28e6c37bd872c3230cc86153</citedby><cites>FETCH-LOGICAL-c311t-1db4d9dbdc53a7198a0749764c31665cd8162f5fb28e6c37bd872c3230cc86153</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,780,784,789,790,23930,23931,25140,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2498762$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8947816$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LINCOLN, S. R</creatorcontrib><creatorcontrib>DOCKERY, J. R</creatorcontrib><creatorcontrib>LONG, C. A</creatorcontrib><creatorcontrib>ROCK, W. A</creatorcontrib><creatorcontrib>COWAN, B. D</creatorcontrib><title>Maternal serum creatine kinase does not predict tubal pregnancy</title><title>Journal of assisted reproduction and genetics</title><addtitle>J Assist Reprod Genet</addtitle><description>Our purpose was to validate prospectively the predictive value of maternal serum creatine kinase in the evaluation of ectopic pregnancy.
Fifty-one consecutive pregnant first-trimester patients who presented for suspected abnormal pregnancy were enrolled. Maternal serum samples were obtained and assayed for creatine kinase. Patients were subsequently evaluated for abnormal pregnancy by serial quantitative hCG levels, transvaginal ultrasonography, and surgery when appropriate. A receiver operating characteristic (ROC) curve was generated comparing intrauterine to extrauterine (ectopic) pregnancy.
Of 51 patients, 18 had an ectopic pregnancy, 16 had a spontaneous abortion, and 17 had an ongoing intrauterine pregnancy. The ROC curve revealed that maternal serum creatine kinase had no ability to predict ectopic pregnancy.
Maternal serum creatine kinase is not a reliable predictor of tubal pregnancy.</description><subject>Biological and medical sciences</subject><subject>Biomarkers - blood</subject><subject>Clinical Enzyme Tests</subject><subject>Creatine Kinase - blood</subject><subject>Diseases of mother, fetus and pregnancy</subject><subject>Female</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Predictive Value of Tests</subject><subject>Pregnancy</subject><subject>Pregnancy Trimester, First</subject><subject>Pregnancy, Ectopic - diagnosis</subject><subject>Pregnancy. Fetus. Placenta</subject><subject>Prospective Studies</subject><subject>Reproducibility of Results</subject><subject>ROC Curve</subject><issn>1058-0468</issn><issn>1573-7330</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEtLxDAUhYMo4zi6cS9kIS6Eah7NayU6OCqMuNF1SZNUqm06Juli_r2RKePq3sv5ONxzADjH6AYjJG4fVoggzkuCD8AcM0ELQSk6zDtiskAll8fgJMYvhJCShM7ATKpSSMzn4O5VJxe87mB0YeyhCU6n1jv43XodHbSDi9APCW6Cs61JMI11hvP16bU321Nw1OguurNpLsDH6vF9-Vys355elvfrwlCMU4FtXVpla2sY1QIrqZEoleBlljlnxuZnSMOamkjHDRW1lYIYSigyRnLM6AJc7Xw3YfgZXUxV30bjuk57N4yxEpJJyqnK4PUONGGIMbim2oS212FbYVT9tVX9t5Xhi8l1rHtn9-hUT9YvJ11Ho7sm5Mht3GOkVFJwQn8Bnm5wAA</recordid><startdate>19961001</startdate><enddate>19961001</enddate><creator>LINCOLN, S. R</creator><creator>DOCKERY, J. R</creator><creator>LONG, C. A</creator><creator>ROCK, W. A</creator><creator>COWAN, B. D</creator><general>Kluwer/Plenum</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19961001</creationdate><title>Maternal serum creatine kinase does not predict tubal pregnancy</title><author>LINCOLN, S. R ; DOCKERY, J. R ; LONG, C. A ; ROCK, W. A ; COWAN, B. D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c311t-1db4d9dbdc53a7198a0749764c31665cd8162f5fb28e6c37bd872c3230cc86153</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Biological and medical sciences</topic><topic>Biomarkers - blood</topic><topic>Clinical Enzyme Tests</topic><topic>Creatine Kinase - blood</topic><topic>Diseases of mother, fetus and pregnancy</topic><topic>Female</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Predictive Value of Tests</topic><topic>Pregnancy</topic><topic>Pregnancy Trimester, First</topic><topic>Pregnancy, Ectopic - diagnosis</topic><topic>Pregnancy. Fetus. Placenta</topic><topic>Prospective Studies</topic><topic>Reproducibility of Results</topic><topic>ROC Curve</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LINCOLN, S. R</creatorcontrib><creatorcontrib>DOCKERY, J. R</creatorcontrib><creatorcontrib>LONG, C. A</creatorcontrib><creatorcontrib>ROCK, W. A</creatorcontrib><creatorcontrib>COWAN, B. D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of assisted reproduction and genetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LINCOLN, S. R</au><au>DOCKERY, J. R</au><au>LONG, C. A</au><au>ROCK, W. A</au><au>COWAN, B. D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Maternal serum creatine kinase does not predict tubal pregnancy</atitle><jtitle>Journal of assisted reproduction and genetics</jtitle><addtitle>J Assist Reprod Genet</addtitle><date>1996-10-01</date><risdate>1996</risdate><volume>13</volume><issue>9</issue><spage>702</spage><epage>704</epage><pages>702-704</pages><issn>1058-0468</issn><eissn>1573-7330</eissn><coden>JARGE4</coden><abstract>Our purpose was to validate prospectively the predictive value of maternal serum creatine kinase in the evaluation of ectopic pregnancy.
Fifty-one consecutive pregnant first-trimester patients who presented for suspected abnormal pregnancy were enrolled. Maternal serum samples were obtained and assayed for creatine kinase. Patients were subsequently evaluated for abnormal pregnancy by serial quantitative hCG levels, transvaginal ultrasonography, and surgery when appropriate. A receiver operating characteristic (ROC) curve was generated comparing intrauterine to extrauterine (ectopic) pregnancy.
Of 51 patients, 18 had an ectopic pregnancy, 16 had a spontaneous abortion, and 17 had an ongoing intrauterine pregnancy. The ROC curve revealed that maternal serum creatine kinase had no ability to predict ectopic pregnancy.
Maternal serum creatine kinase is not a reliable predictor of tubal pregnancy.</abstract><cop>New York, NY</cop><pub>Kluwer/Plenum</pub><pmid>8947816</pmid><doi>10.1007/BF02066421</doi><tpages>3</tpages></addata></record> |
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| source | MEDLINE; SpringerNature Journals |
| subjects | Biological and medical sciences Biomarkers - blood Clinical Enzyme Tests Creatine Kinase - blood Diseases of mother, fetus and pregnancy Female Gynecology. Andrology. Obstetrics Humans Medical sciences Predictive Value of Tests Pregnancy Pregnancy Trimester, First Pregnancy, Ectopic - diagnosis Pregnancy. Fetus. Placenta Prospective Studies Reproducibility of Results ROC Curve |
| title | Maternal serum creatine kinase does not predict tubal pregnancy |
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