Humoral immunity and regulation of intrapulmonary growth of Legionella pneumophila in the immunocompetent host

The potential role of humoral immunity in regulating intrapulmonary growth of Legionella pneumophila in the immunocompetent host was investigated using a murine model of Legionnaires' disease. Intratracheal inoculation of A/J mice with a virulent strain of L. pneumophila (10(6) bacteria per mou...

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Veröffentlicht in:	The Journal of immunology (1950) 1996-12, Vol.157 (11), p.5002-5008
Hauptverfasser:	Brieland, JK, Heath, LA, Huffnagle, GB, Remick, DG, McClain, MS, Hurley, MC, Kunkel, RK, Fantone, JC, Engleberg, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Bacterial - biosynthesis Complement System Proteins - metabolism Female Immunocompetence Legionella pneumophila Legionella pneumophila - growth & development Legionella pneumophila - immunology Legionnaires' Disease - etiology Legionnaires' Disease - immunology Legionnaires' Disease - microbiology Lung - immunology Lung - microbiology Macrophages, Alveolar - immunology Mice Mice, Inbred A Opsonin Proteins - metabolism Phagocytosis Time Factors
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