Photochemical decontamination of blood components containing hepatitis B and non-A, non-B virus

Diluted plasma samples containing 10(2), 10(3), 10(4), and 10(5) chimpanzee infectious doses (CID) of a human non-A, non-B hepatitis virus (NANBV) were treated with a combination of two psoralen compounds, 4'-aminomethyl-4,5',8-trimethylpsoralen and 4,5',8-trimethylpsoralen, and expos...

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Veröffentlicht in:	The Lancet (British edition) 1988-12, Vol.2 (8626-8627), p.1446-1450
Hauptverfasser:	Alter, H J, Creagan, R P, Morel, P A, Wiesehahn, G P, Dorman, B P, Corash, L, Smith, G C, Popper, H, Eichberg, J W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood - microbiology Decontamination - methods Factor VIII - analysis Hepatitis B virus - drug effects Hepatitis B virus - radiation effects Hepatitis Viruses - drug effects Hepatitis Viruses - radiation effects Humans Pan troglodytes PUVA Therapy Trioxsalen - analogs & derivatives Trioxsalen - pharmacology Virus Replication - drug effects Virus Replication - radiation effects
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